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Page 1
Distinct transcriptome architectures underlying lupus establishment and exacerbation.
Nakano M, Ota M, Takeshima Y, Iwasaki Y, Hatano H, Nagafuchi Y, Itamiya T, Maeda J, Yoshida R, Yamada S, Nishiwaki A, Takahashi H, Takahashi H, Akutsu Y, Kusuda T, Suetsugu H, Liu L, Kim K, Yin X, Bang SY, Cui Y, Lee HS, Shoda H, Zhang X, Bae SC, Terao C, Yamamoto K, Okamura T, Ishigaki K, Fujio K. Nakano M, et al. Among authors: takeshima y. Cell. 2022 Sep 1;185(18):3375-3389.e21. doi: 10.1016/j.cell.2022.07.021. Epub 2022 Aug 22. Cell. 2022. PMID: 35998627 Free article.
Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases.
Ota M, Nagafuchi Y, Hatano H, Ishigaki K, Terao C, Takeshima Y, Yanaoka H, Kobayashi S, Okubo M, Shirai H, Sugimori Y, Maeda J, Nakano M, Yamada S, Yoshida R, Tsuchiya H, Tsuchida Y, Akizuki S, Yoshifuji H, Ohmura K, Mimori T, Yoshida K, Kurosaka D, Okada M, Setoguchi K, Kaneko H, Ban N, Yabuki N, Matsuki K, Mutoh H, Oyama S, Okazaki M, Tsunoda H, Iwasaki Y, Sumitomo S, Shoda H, Kochi Y, Okada Y, Yamamoto K, Okamura T, Fujio K. Ota M, et al. Among authors: takeshima y. Cell. 2021 May 27;184(11):3006-3021.e17. doi: 10.1016/j.cell.2021.03.056. Epub 2021 May 1. Cell. 2021. PMID: 33930287 Free article.
Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells.
Mimitou EP, Lareau CA, Chen KY, Zorzetto-Fernandes AL, Hao Y, Takeshima Y, Luo W, Huang TS, Yeung BZ, Papalexi E, Thakore PI, Kibayashi T, Wing JB, Hata M, Satija R, Nazor KL, Sakaguchi S, Ludwig LS, Sankaran VG, Regev A, Smibert P. Mimitou EP, et al. Among authors: takeshima y. Nat Biotechnol. 2021 Oct;39(10):1246-1258. doi: 10.1038/s41587-021-00927-2. Epub 2021 Jun 3. Nat Biotechnol. 2021. PMID: 34083792 Free PMC article.
Myasthenia gravis-specific aberrant neuromuscular gene expression by medullary thymic epithelial cells in thymoma.
Yasumizu Y, Ohkura N, Murata H, Kinoshita M, Funaki S, Nojima S, Kido K, Kohara M, Motooka D, Okuzaki D, Suganami S, Takeuchi E, Nakamura Y, Takeshima Y, Arai M, Tada S, Okumura M, Morii E, Shintani Y, Sakaguchi S, Okuno T, Mochizuki H. Yasumizu Y, et al. Among authors: takeshima y. Nat Commun. 2022 Jul 22;13(1):4230. doi: 10.1038/s41467-022-31951-8. Nat Commun. 2022. PMID: 35869073 Free PMC article.
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity.
Edahiro R, Shirai Y, Takeshima Y, Sakakibara S, Yamaguchi Y, Murakami T, Morita T, Kato Y, Liu YC, Motooka D, Naito Y, Takuwa A, Sugihara F, Tanaka K, Wing JB, Sonehara K, Tomofuji Y; Japan COVID-19 Task Force; Namkoong H, Tanaka H, Lee H, Fukunaga K, Hirata H, Takeda Y, Okuzaki D, Kumanogoh A, Okada Y. Edahiro R, et al. Among authors: takeshima y. Nat Genet. 2023 May;55(5):753-767. doi: 10.1038/s41588-023-01375-1. Epub 2023 Apr 24. Nat Genet. 2023. PMID: 37095364 Free PMC article.
Immunomics analysis of rheumatoid arthritis identified precursor dendritic cells as a key cell subset of treatment resistance.
Yamada S, Nagafuchi Y, Wang M, Ota M, Hatano H, Takeshima Y, Okubo M, Kobayashi S, Sugimori Y, Masahiro N, Yoshida R, Hanata N, Suwa Y, Tsuchida Y, Iwasaki Y, Sumitomo S, Kubo K, Shimane K, Setoguchi K, Azuma T, Kanda H, Shoda H, Zhang X, Yamamoto K, Ishigaki K, Okamura T, Fujio K. Yamada S, et al. Among authors: takeshima y. Ann Rheum Dis. 2023 Jun;82(6):809-819. doi: 10.1136/ard-2022-223645. Epub 2023 Mar 14. Ann Rheum Dis. 2023. PMID: 36918189 Free PMC article.
Basic mechanism of immune system activation by mitochondria.
Iwasaki Y, Takeshima Y, Fujio K. Iwasaki Y, et al. Among authors: takeshima y. Immunol Med. 2020 Dec;43(4):142-147. doi: 10.1080/25785826.2020.1756609. Epub 2020 May 12. Immunol Med. 2020. PMID: 32393116 Review.
Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases.
Yasumizu Y, Takeuchi D, Morimoto R, Takeshima Y, Okuno T, Kinoshita M, Morita T, Kato Y, Wang M, Motooka D, Okuzaki D, Nakamura Y, Mikami N, Arai M, Zhang X, Kumanogoh A, Mochizuki H, Ohkura N, Sakaguchi S. Yasumizu Y, et al. Among authors: takeshima y. Cell Genom. 2024 Feb 14;4(2):100473. doi: 10.1016/j.xgen.2023.100473. Epub 2024 Jan 3. Cell Genom. 2024. PMID: 38359792 Free PMC article.
21 results