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2014 1
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Page 1
Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Victorelli S, et al. Among authors: zacharioudakis e. Nature. 2023 Oct;622(7983):627-636. doi: 10.1038/s41586-023-06621-4. Epub 2023 Oct 11. Nature. 2023. PMID: 37821702 Free PMC article.
Mitochondrial dynamics proteins as emerging drug targets.
Zacharioudakis E, Gavathiotis E. Zacharioudakis E, et al. Trends Pharmacol Sci. 2023 Feb;44(2):112-127. doi: 10.1016/j.tips.2022.11.004. Epub 2022 Dec 7. Trends Pharmacol Sci. 2023. PMID: 36496299 Free PMC article. Review.
Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
Glytsou C, Chen X, Zacharioudakis E, Al-Santli W, Zhou H, Nadorp B, Lee S, Lasry A, Sun Z, Papaioannou D, Cammer M, Wang K, Zal T, Zal MA, Carter BZ, Ishizawa J, Tibes R, Tsirigos A, Andreeff M, Gavathiotis E, Aifantis I. Glytsou C, et al. Among authors: zacharioudakis e. Cancer Discov. 2023 Jul 7;13(7):1656-1677. doi: 10.1158/2159-8290.CD-22-0601. Cancer Discov. 2023. PMID: 37088914 Free PMC article.
Modulating mitofusins to control mitochondrial function and signaling.
Zacharioudakis E, Agianian B, Kumar Mv V, Biris N, Garner TP, Rabinovich-Nikitin I, Ouchida AT, Margulets V, Nordstrøm LU, Riley JS, Dolgalev I, Chen Y, Wittig AJH, Pekson R, Mathew C, Wei P, Tsirigos A, Tait SWG, Kirshenbaum LA, Kitsis RN, Gavathiotis E. Zacharioudakis E, et al. Nat Commun. 2022 Jul 7;13(1):3775. doi: 10.1038/s41467-022-31324-1. Nat Commun. 2022. PMID: 35798717 Free PMC article.
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Victorelli S, et al. Among authors: zacharioudakis e. Nature. 2024 Jan;625(7995):E15. doi: 10.1038/s41586-023-07002-7. Nature. 2024. PMID: 38168624 Free PMC article. No abstract available.
Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Carling GK, Fan L, Foxe NR, Norman K, Ye P, Wong MY, Zhu D, Yu F, Xu J, Yarahmady A, Chen H, Huang Y, Amin S, Zacharioudakis E, Chen X, Holtzman DM, Mok SA, Gavathiotis E, Sinha SC, Cheng F, Luo W, Gong S, Gan L. Carling GK, et al. Among authors: zacharioudakis e. bioRxiv [Preprint]. 2024 Jan 25:2024.01.24.577107. doi: 10.1101/2024.01.24.577107. bioRxiv. 2024. PMID: 38328219 Free PMC article. Preprint.
Chromatin Regulates Genome Targeting with Cisplatin.
Zacharioudakis E, Agarwal P, Bartoli A, Abell N, Kunalingam L, Bergoglio V, Xhemalce B, Miller KM, Rodriguez R. Zacharioudakis E, et al. Angew Chem Int Ed Engl. 2017 Jun 1;56(23):6483-6487. doi: 10.1002/anie.201701144. Epub 2017 May 5. Angew Chem Int Ed Engl. 2017. PMID: 28474855 Free PMC article.
Eltrombopag directly inhibits BAX and prevents cell death.
Spitz AZ, Zacharioudakis E, Reyna DE, Garner TP, Gavathiotis E. Spitz AZ, et al. Among authors: zacharioudakis e. Nat Commun. 2021 Feb 18;12(1):1134. doi: 10.1038/s41467-021-21224-1. Nat Commun. 2021. PMID: 33602934 Free PMC article.
17 results