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RNA Is a Double-Edged Sword in ALS Pathogenesis.
Zaepfel BL, Rothstein JD. Zaepfel BL, et al. Front Cell Neurosci. 2021 Jul 19;15:708181. doi: 10.3389/fncel.2021.708181. eCollection 2021. Front Cell Neurosci. 2021. PMID: 34349625 Free PMC article. Review.
Nuclear Pore Dysfunction in Neurodegeneration.
Spead O, Zaepfel BL, Rothstein JD. Spead O, et al. Among authors: zaepfel bl. Neurotherapeutics. 2022 Jul;19(4):1050-1060. doi: 10.1007/s13311-022-01293-w. Epub 2022 Sep 7. Neurotherapeutics. 2022. PMID: 36070178 Free PMC article. Review.
Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS.
Coyne AN, Lorenzini I, Chou CC, Torvund M, Rogers RS, Starr A, Zaepfel BL, Levy J, Johannesmeyer J, Schwartz JC, Nishimune H, Zinsmaier K, Rossoll W, Sattler R, Zarnescu DC. Coyne AN, et al. Among authors: zaepfel bl. Cell Rep. 2017 Oct 3;21(1):110-125. doi: 10.1016/j.celrep.2017.09.028. Cell Rep. 2017. PMID: 28978466 Free PMC article.
Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation.
Coyne AN, Yamada SB, Siddegowda BB, Estes PS, Zaepfel BL, Johannesmeyer JS, Lockwood DB, Pham LT, Hart MP, Cassel JA, Freibaum B, Boehringer AV, Taylor JP, Reitz AB, Gitler AD, Zarnescu DC. Coyne AN, et al. Among authors: zaepfel bl. Hum Mol Genet. 2015 Dec 15;24(24):6886-98. doi: 10.1093/hmg/ddv389. Epub 2015 Sep 18. Hum Mol Genet. 2015. PMID: 26385636 Free PMC article.