Zebala JA - Search Results

1

Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast.

Sinha VC, Rinkenbaugh AL, Xu M, Zhou X, Zhang X, Jeter-Jones S, Shao J, Qi Y, Zebala JA, Maeda DY, McAllister F, Piwnica-Worms H. Sinha VC, et al. Among authors: zebala ja. Nat Commun. 2021 Aug 18;12(1):5024. doi: 10.1038/s41467-021-25240-z. Nat Commun. 2021. PMID: 34408137 Free PMC article.

2

Glutathione S-transferase P1-1 expression modulates sensitivity of human kidney 293 cells to photodynamic therapy with hypericin.

Dabrowski MJ, Maeda D, Zebala J, Lu WD, Mahajan S, Kavanagh TJ, Atkins WM. Dabrowski MJ, et al. Arch Biochem Biophys. 2006 May 15;449(1-2):94-103. doi: 10.1016/j.abb.2006.02.009. Epub 2006 Mar 3. Arch Biochem Biophys. 2006. PMID: 16546115 Free PMC article.

3

Bivalent inhibitors of glutathione S-transferase: the effect of spacer length on isozyme selectivity.

Maeda DY, Mahajan SS, Atkins WM, Zebala JA. Maeda DY, et al. Among authors: zebala ja. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3780-3. doi: 10.1016/j.bmcl.2006.04.041. Epub 2006 May 3. Bioorg Med Chem Lett. 2006. PMID: 16675217

4

Snap-to-it probes: chelate-constrained nucleobase oligomers with enhanced binding specificity.

Morgan JR, Lyon RP, Maeda DY, Zebala JA. Morgan JR, et al. Among authors: zebala ja. Nucleic Acids Res. 2008 Jun;36(11):3522-30. doi: 10.1093/nar/gkn219. Epub 2008 Apr 29. Nucleic Acids Res. 2008. PMID: 18448470 Free PMC article.

5

Nicotinamide glycolates antagonize CXCR2 activity through an intracellular mechanism.

Maeda DY, Quinn MT, Schepetkin IA, Kirpotina LN, Zebala JA. Maeda DY, et al. Among authors: zebala ja. J Pharmacol Exp Ther. 2010 Jan;332(1):145-52. doi: 10.1124/jpet.109.159020. Epub 2009 Sep 24. J Pharmacol Exp Ther. 2010. PMID: 19779130 Free PMC article.

6

Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporter.

Menter A, Thrash B, Cherian C, Matherly LH, Wang L, Gangjee A, Morgan JR, Maeda DY, Schuler AD, Kahn SJ, Zebala JA. Menter A, et al. Among authors: zebala ja. J Pharmacol Exp Ther. 2012 Sep;342(3):696-708. doi: 10.1124/jpet.112.195479. Epub 2012 May 31. J Pharmacol Exp Ther. 2012. PMID: 22653877 Free PMC article. Clinical Trial.

7

Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2.

Maeda DY, Peck AM, Schuler AD, Quinn MT, Kirpotina LN, Wicomb WN, Fan GH, Zebala JA. Maeda DY, et al. Among authors: zebala ja. J Med Chem. 2014 Oct 23;57(20):8378-97. doi: 10.1021/jm500827t. Epub 2014 Oct 8. J Med Chem. 2014. PMID: 25254640 Free PMC article.

8

Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding model.

Maeda DY, Peck AM, Schuler AD, Quinn MT, Kirpotina LN, Wicomb WN, Auten RL, Gundla R, Zebala JA. Maeda DY, et al. Among authors: zebala ja. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2280-4. doi: 10.1016/j.bmcl.2015.04.041. Epub 2015 Apr 23. Bioorg Med Chem Lett. 2015. PMID: 25933594 Free PMC article.

9

Boronic acid-containing aminopyridine- and aminopyrimidinecarboxamide CXCR1/2 antagonists: Optimization of aqueous solubility and oral bioavailability.

Schuler AD, Engles CA, Maeda DY, Quinn MT, Kirpotina LN, Wicomb WN, Mason SN, Auten RL, Zebala JA. Schuler AD, et al. Among authors: zebala ja. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7. doi: 10.1016/j.bmcl.2015.07.090. Epub 2015 Jul 30. Bioorg Med Chem Lett. 2015. PMID: 26248802 Free PMC article.

10

Effective combinatorial immunotherapy for castration-resistant prostate cancer.

Lu X, Horner JW, Paul E, Shang X, Troncoso P, Deng P, Jiang S, Chang Q, Spring DJ, Sharma P, Zebala JA, Maeda DY, Wang YA, DePinho RA. Lu X, et al. Among authors: zebala ja. Nature. 2017 Mar 30;543(7647):728-732. doi: 10.1038/nature21676. Epub 2017 Mar 20. Nature. 2017. PMID: 28321130 Free PMC article.

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