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CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.
Putz EM, Gotthardt D, Hoermann G, Csiszar A, Wirth S, Berger A, Straka E, Rigler D, Wallner B, Jamieson AM, Pickl WF, Zebedin-Brandl EM, Müller M, Decker T, Sexl V. Putz EM, et al. Among authors: zebedin brandl em. Cell Rep. 2013 Aug 15;4(3):437-44. doi: 10.1016/j.celrep.2013.07.012. Epub 2013 Aug 8. Cell Rep. 2013. PMID: 23933255 Free PMC article.
Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity.
Putz EM, Majoros A, Gotthardt D, Prchal-Murphy M, Zebedin-Brandl EM, Fux DA, Schlattl A, Schreiber RD, Carotta S, Müller M, Gerner C, Decker T, Sexl V. Putz EM, et al. Among authors: zebedin brandl em. Oncoimmunology. 2016 May 19;5(9):e1186314. doi: 10.1080/2162402X.2016.1186314. eCollection 2016. Oncoimmunology. 2016. PMID: 27757297 Free PMC article.
PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.
Putz EM, Prchal-Murphy M, Simma OA, Forster F, Koenig X, Stockinger H, Piekorz RP, Freissmuth M, Müller M, Sexl V, Zebedin-Brandl E. Putz EM, et al. PLoS One. 2012;7(7):e40852. doi: 10.1371/journal.pone.0040852. Epub 2012 Jul 13. PLoS One. 2012. PMID: 22808277 Free PMC article.
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance.
Mizutani T, Neugebauer N, Putz EM, Moritz N, Simma O, Zebedin-Brandl E, Gotthardt D, Warsch W, Eckelhart E, Kantner HP, Kalinke U, Lienenklaus S, Weiss S, Strobl B, Müller M, Sexl V, Stoiber D. Mizutani T, et al. Oncoimmunology. 2012 Oct 1;1(7):1027-1037. doi: 10.4161/onci.21284. Oncoimmunology. 2012. PMID: 23170251 Free PMC article.
Targeting PI3Kδ: One man's meat is another man's poison.
Prchal-Murphy M, Putz EM, Freissmuth M, Sexl V, Zebedin-Brandl E. Prchal-Murphy M, et al. Oncoimmunology. 2013 Jan 1;2(1):e22272. doi: 10.4161/onci.22272. Oncoimmunology. 2013. PMID: 23482629 Free PMC article.
Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
Themanns M, Mueller KM, Kessler SM, Golob-Schwarzl N, Mohr T, Kaltenecker D, Bourgeais J, Paier-Pourani J, Friedbichler K, Schneller D, Schlederer M, Zebedin-Brandl E, Terracciano LM, Han X, Kenner L, Wagner KU, Mikulits W, Kozlov AV, Heim MH, Gouilleux F, Haybaeck J, Moriggl R. Themanns M, et al. Sci Rep. 2016 Oct 7;6:34719. doi: 10.1038/srep34719. Sci Rep. 2016. PMID: 27713471 Free PMC article.
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