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Vinculin controls talin engagement with the actomyosin machinery.
Atherton P, Stutchbury B, Wang DY, Jethwa D, Tsang R, Meiler-Rodriguez E, Wang P, Bate N, Zent R, Barsukov IL, Goult BT, Critchley DR, Ballestrem C. Atherton P, et al. Among authors: zent r. Nat Commun. 2015 Dec 4;6:10038. doi: 10.1038/ncomms10038. Nat Commun. 2015. PMID: 26634421 Free PMC article.
β1 integrin NPXY motifs regulate kidney collecting-duct development and maintenance by induced-fit interactions with cytosolic proteins.
Mathew S, Lu Z, Palamuttam RJ, Mernaugh G, Hadziselimovic A, Chen J, Bulus N, Gewin LS, Voehler M, Meves A, Ballestrem C, Fässler R, Pozzi A, Sanders CR, Zent R. Mathew S, et al. Among authors: zent r. Mol Cell Biol. 2012 Oct;32(20):4080-91. doi: 10.1128/MCB.00568-12. Epub 2012 Aug 6. Mol Cell Biol. 2012. PMID: 22869523 Free PMC article.
Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.
Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S. Tian X, et al. Among authors: zent r. J Clin Invest. 2014 Mar;124(3):1098-113. doi: 10.1172/JCI69778. Epub 2014 Feb 17. J Clin Invest. 2014. PMID: 24531545 Free PMC article.
Extracellular rigidity sensing by talin isoform-specific mechanical linkages.
Austen K, Ringer P, Mehlich A, Chrostek-Grashoff A, Kluger C, Klingner C, Sabass B, Zent R, Rief M, Grashoff C. Austen K, et al. Among authors: zent r. Nat Cell Biol. 2015 Dec;17(12):1597-606. doi: 10.1038/ncb3268. Epub 2015 Nov 2. Nat Cell Biol. 2015. PMID: 26523364 Free PMC article.
Vinculin is required to maintain glomerular barrier integrity.
Lausecker F, Tian X, Inoue K, Wang Z, Pedigo CE, Hassan H, Liu C, Zimmer M, Jinno S, Huckle AL, Hamidi H, Ross RS, Zent R, Ballestrem C, Lennon R, Ishibe S. Lausecker F, et al. Among authors: zent r. Kidney Int. 2018 Mar;93(3):643-655. doi: 10.1016/j.kint.2017.09.021. Epub 2017 Dec 12. Kidney Int. 2018. PMID: 29241625 Free PMC article.
The tail of integrins, talin, and kindlins.
Moser M, Legate KR, Zent R, Fässler R. Moser M, et al. Among authors: zent r. Science. 2009 May 15;324(5929):895-9. doi: 10.1126/science.1163865. Science. 2009. PMID: 19443776 Review.
195 results