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Crystal structure of the α1B-adrenergic receptor reveals molecular determinants of selective ligand recognition.
Deluigi M, Morstein L, Schuster M, Klenk C, Merklinger L, Cridge RR, de Zhang LA, Klipp A, Vacca S, Vaid TM, Mittl PRE, Egloff P, Eberle SA, Zerbe O, Chalmers DK, Scott DJ, Plückthun A. Deluigi M, et al. Among authors: zerbe o. Nat Commun. 2022 Jan 19;13(1):382. doi: 10.1038/s41467-021-27911-3. Nat Commun. 2022. PMID: 35046410 Free PMC article.
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
Reichen C, Hansen S, Forzani C, Honegger A, Fleishman SJ, Zhou T, Parmeggiani F, Ernst P, Madhurantakam C, Ewald C, Mittl PRE, Zerbe O, Baker D, Caflisch A, Plückthun A. Reichen C, et al. Among authors: zerbe o. J Mol Biol. 2016 Nov 6;428(22):4467-4489. doi: 10.1016/j.jmb.2016.09.012. Epub 2016 Sep 21. J Mol Biol. 2016. PMID: 27664438
Peptide-Guided Assembly of Repeat Protein Fragments.
Michel E, Plückthun A, Zerbe O. Michel E, et al. Among authors: zerbe o. Angew Chem Int Ed Engl. 2018 Apr 16;57(17):4576-4579. doi: 10.1002/anie.201713377. Epub 2018 Mar 13. Angew Chem Int Ed Engl. 2018. PMID: 29480529 Free article.
Peptide binding affinity redistributes preassembled repeat protein fragments.
Michel E, Plückthun A, Zerbe O. Michel E, et al. Among authors: zerbe o. Biol Chem. 2019 Feb 25;400(3):395-404. doi: 10.1515/hsz-2018-0355. Biol Chem. 2019. PMID: 30517075 Free article.
Complementary fragments of dArmRPs obtained by splitting the protein between helices H1 and H2 of an internal module show conditional and specific assembly only in the presence of a target peptide (Michel, E., Pluckthun, A., and Zerbe, O. (2018). Peptide-guided asse …
Complementary fragments of dArmRPs obtained by splitting the protein between helices H1 and H2 of an internal module show conditional and sp …
126 results