Zha S - Search Results

1

Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.

Schvartzman JM, Forsyth G, Walch H, Chatila W, Taglialatela A, Lee BJ, Zhu X, Gershik S, Cimino FV, Santella A, Menghrajani K, Ciccia A, Koche R, Sánchez-Vega F, Zha S, Thompson CB. Schvartzman JM, et al. Among authors: zha s. Mol Cell. 2023 Jul 6;83(13):2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026. Epub 2023 Jun 12. Mol Cell. 2023. PMID: 37311462

2

Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency.

Avagyan S, Churchill M, Yamamoto K, Crowe JL, Li C, Lee BJ, Zheng T, Mukherjee S, Zha S. Avagyan S, et al. Among authors: zha s. Blood. 2014 Sep 4;124(10):1622-5. doi: 10.1182/blood-2014-05-574863. Epub 2014 Jul 29. Blood. 2014. PMID: 25075129 Free PMC article.

3

Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice.

Yamamoto K, Lee BJ, Li C, Dubois RL, Hobeika E, Bhagat G, Zha S. Yamamoto K, et al. Among authors: zha s. Leukemia. 2015 Jun;29(6):1414-24. doi: 10.1038/leu.2015.41. Epub 2015 Feb 13. Leukemia. 2015. PMID: 25676421 Free PMC article.

4

Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency.

Jiang W, Lee BJ, Li C, Dubois RL, Gostissa M, Alt FW, Zha S. Jiang W, et al. Among authors: zha s. Blood. 2015 Apr 23;125(17):2665-8. doi: 10.1182/blood-2015-01-622621. Epub 2015 Feb 26. Blood. 2015. PMID: 25721125 Free PMC article.

5

Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.

Jiang W, Crowe JL, Liu X, Nakajima S, Wang Y, Li C, Lee BJ, Dubois RL, Liu C, Yu X, Lan L, Zha S. Jiang W, et al. Among authors: zha s. Mol Cell. 2015 Apr 2;58(1):172-85. doi: 10.1016/j.molcel.2015.02.024. Epub 2015 Mar 26. Mol Cell. 2015. PMID: 25818648 Free PMC article.

6

Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas.

Pinkney KA, Jiang W, Lee BJ, Loredan DG, Li C, Bhagat G, Zha S. Pinkney KA, et al. Among authors: zha s. J Hematol Oncol. 2015 Jul 30;8:94. doi: 10.1186/s13045-015-0191-8. J Hematol Oncol. 2015. PMID: 26219558 Free PMC article.

7

Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors.

Yamamoto K, Wang J, Sprinzen L, Xu J, Haddock CJ, Li C, Lee BJ, Loredan DG, Jiang W, Vindigni A, Wang D, Rabadan R, Zha S. Yamamoto K, et al. Among authors: zha s. Elife. 2016 Jun 15;5:e14709. doi: 10.7554/eLife.14709. Elife. 2016. PMID: 27304073 Free PMC article.

8

Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.

Zhou Y, Lee JH, Jiang W, Crowe JL, Zha S, Paull TT. Zhou Y, et al. Among authors: zha s. Mol Cell. 2017 Jan 5;65(1):91-104. doi: 10.1016/j.molcel.2016.11.004. Epub 2016 Dec 8. Mol Cell. 2017. PMID: 27939942 Free PMC article.

9

PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice.

Liu X, Shao Z, Jiang W, Lee BJ, Zha S. Liu X, et al. Among authors: zha s. Nat Commun. 2017 Jan 4;8:13816. doi: 10.1038/ncomms13816. Nat Commun. 2017. PMID: 28051062 Free PMC article.

10

MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.

Hung PJ, Johnson B, Chen BR, Byrum AK, Bredemeyer AL, Yewdell WT, Johnson TE, Lee BJ, Deivasigamani S, Hindi I, Amatya P, Gross ML, Paull TT, Pisapia DJ, Chaudhuri J, Petrini JJH, Mosammaparast N, Amarasinghe GK, Zha S, Tyler JK, Sleckman BP. Hung PJ, et al. Among authors: zha s. Mol Cell. 2018 Jul 19;71(2):332-342.e8. doi: 10.1016/j.molcel.2018.06.018. Epub 2018 Jul 12. Mol Cell. 2018. PMID: 30017584 Free PMC article.

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