Zhang L - Search Results

1

Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe.

Zhang G, Dong Z, Gimple RC, Wolin A, Wu Q, Qiu Z, Wood LM, Shen JZ, Jiang L, Zhao L, Lv D, Prager BC, Kim LJY, Wang X, Zhang L, Anderson RL, Moore JK, Bao S, Keller TH, Lin G, Kang C, Hamerlik P, Zhao R, Ford HL, Rich JN. Zhang G, et al. Among authors: zhang l. J Exp Med. 2021 Nov 1;218(11):e20202669. doi: 10.1084/jem.20202669. Epub 2021 Oct 7. J Exp Med. 2021. PMID: 34617969 Free PMC article.

2

Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants.

Zhang L, Shen J, Guarnieri MT, Heroux A, Yang K, Zhao R. Zhang L, et al. Protein Sci. 2007 Jun;16(6):1024-31. doi: 10.1110/ps.072872007. Epub 2007 May 1. Protein Sci. 2007. PMID: 17473007 Free PMC article.

3

Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factor.

Shen J, Zhang L, Zhao R. Shen J, et al. Among authors: zhang l. J Biol Chem. 2007 Aug 3;282(31):22544-50. doi: 10.1074/jbc.M702304200. Epub 2007 Jun 11. J Biol Chem. 2007. PMID: 17562711 Free article.

4

The Hsp90 inhibitor radicicol interacts with the ATP-binding pocket of bacterial sensor kinase PhoQ.

Guarnieri MT, Zhang L, Shen J, Zhao R. Guarnieri MT, et al. Among authors: zhang l. J Mol Biol. 2008 May 23;379(1):82-93. doi: 10.1016/j.jmb.2008.03.036. Epub 2008 Mar 26. J Mol Biol. 2008. PMID: 18440021

5

Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins.

Yang K, Zhang L, Xu T, Heroux A, Zhao R. Yang K, et al. Among authors: zhang l. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13817-22. doi: 10.1073/pnas.0805960105. Epub 2008 Sep 8. Proc Natl Acad Sci U S A. 2008. PMID: 18779563 Free PMC article.

6

Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2.

Zhang L, Xu T, Maeder C, Bud LO, Shanks J, Nix J, Guthrie C, Pleiss JA, Zhao R. Zhang L, et al. Nat Struct Mol Biol. 2009 Jul;16(7):731-9. doi: 10.1038/nsmb.1625. Epub 2009 Jun 14. Nat Struct Mol Biol. 2009. PMID: 19525970 Free PMC article.

7

Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly.

Li X, Zhang W, Xu T, Ramsey J, Zhang L, Hill R, Hansen KC, Hesselberth JR, Zhao R. Li X, et al. Among authors: zhang l, zhang w. Nucleic Acids Res. 2013 Apr 1;41(6):3805-18. doi: 10.1093/nar/gkt062. Epub 2013 Feb 7. Nucleic Acids Res. 2013. PMID: 23393194 Free PMC article.

8

Structural analyses of the pre-mRNA splicing machinery.

Zhang L, Li X, Zhao R. Zhang L, et al. Protein Sci. 2013 Jun;22(6):677-92. doi: 10.1002/pro.2266. Epub 2013 May 8. Protein Sci. 2013. PMID: 23592432 Free PMC article. Review.

9

Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding.

Zhang L, Li X, Hill RC, Qiu Y, Zhang W, Hansen KC, Zhao R. Zhang L, et al. Among authors: zhang w. Nucleic Acids Res. 2015 Mar 31;43(6):3286-97. doi: 10.1093/nar/gkv062. Epub 2015 Feb 10. Nucleic Acids Res. 2015. PMID: 25670679 Free PMC article.

10

Understanding pre-mRNA splicing through crystallography.

Espinosa S, Zhang L, Li X, Zhao R. Espinosa S, et al. Among authors: zhang l. Methods. 2017 Aug 1;125:55-62. doi: 10.1016/j.ymeth.2017.04.023. Epub 2017 May 12. Methods. 2017. PMID: 28506657 Free PMC article. Review.

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