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The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy.
Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, Vondriska TM, Li G, Deb A, Srivastava D, Yang HT, Xiao X, Li H, Wang Y. Wang Z, et al. Among authors: zhang p, zhang xj. Nat Med. 2016 Oct;22(10):1131-1139. doi: 10.1038/nm.4179. Epub 2016 Sep 12. Nat Med. 2016. PMID: 27618650 Free PMC article.
Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.
Wang PX, Ji YX, Zhang XJ, Zhao LP, Yan ZZ, Zhang P, Shen LJ, Yang X, Fang J, Tian S, Zhu XY, Gong J, Zhang X, Wei QF, Wang Y, Li J, Wan L, Xie Q, She ZG, Wang Z, Huang Z, Li H. Wang PX, et al. Among authors: zhang p, zhang xj, zhang x. Nat Med. 2017 Apr;23(4):439-449. doi: 10.1038/nm.4290. Epub 2017 Feb 20. Nat Med. 2017. PMID: 28218919
Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.
Zhao GN, Zhang P, Gong J, Zhang XJ, Wang PX, Yin M, Jiang Z, Shen LJ, Ji YX, Tong J, Wang Y, Wei QF, Wang Y, Zhu XY, Zhang X, Fang J, Xie Q, She ZG, Wang Z, Huang Z, Li H. Zhao GN, et al. Among authors: zhang p, zhang xj, zhang x. Nat Med. 2017 Jun;23(6):742-752. doi: 10.1038/nm.4334. Epub 2017 May 8. Nat Med. 2017. PMID: 28481357
The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.
Ji YX, Huang Z, Yang X, Wang X, Zhao LP, Wang PX, Zhang XJ, Alves-Bezerra M, Cai L, Zhang P, Lu YX, Bai L, Gao MM, Zhao H, Tian S, Wang Y, Huang ZX, Zhu XY, Zhang Y, Gong J, She ZG, Li F, Cohen DE, Li H. Ji YX, et al. Among authors: zhang p, zhang xj, zhang y. Nat Med. 2018 Feb;24(2):213-223. doi: 10.1038/nm.4461. Epub 2018 Jan 1. Nat Med. 2018. PMID: 29291351
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