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Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response.
Zhang P, Kitchen-Smith I, Xiong L, Stracquadanio G, Brown K, Richter PH, Wallace MD, Bond E, Sahgal N, Moore S, Nornes S, De Val S, Surakhy M, Sims D, Wang X, Bell DA, Zeron-Medina J, Jiang Y, Ryan AJ, Selfe JL, Shipley J, Kar S, Pharoah PD, Loveday C, Jansen R, Grochola LF, Palles C, Protheroe A, Millar V, Ebner DV, Pagadala M, Blagden SP, Maughan TS, Domingo E, Tomlinson I, Turnbull C, Carter H, Bond GL. Zhang P, et al. Cancer Res. 2021 Apr 1;81(7):1667-1680. doi: 10.1158/0008-5472.CAN-20-0177. Epub 2021 Feb 8. Cancer Res. 2021. PMID: 33558336 Free PMC article.
The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Stracquadanio G, Wang X, Wallace MD, Grawenda AM, Zhang P, Hewitt J, Zeron-Medina J, Castro-Giner F, Tomlinson IP, Goding CR, Cygan KJ, Fairbrother WG, Thomas LF, Sætrom P, Gemignani F, Landi S, Schuster-Böckler B, Bell DA, Bond GL. Stracquadanio G, et al. Among authors: zhang p. Nat Rev Cancer. 2016 Apr;16(4):251-65. doi: 10.1038/nrc.2016.15. Nat Rev Cancer. 2016. PMID: 27009395 Free PMC article. Review.
iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition.
Chen S, Wu J, Zhong S, Li Y, Zhang P, Ma J, Ren J, Tan Y, Wang Y, Au KF, Siebold C, Bond GL, Chen Z, Lu M, Jones EY, Lu X. Chen S, et al. Among authors: zhang p. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17470-17479. doi: 10.1073/pnas.1909393116. Epub 2019 Aug 8. Proc Natl Acad Sci U S A. 2019. PMID: 31395738 Free PMC article.
JMCB Symposium 2019: The Legend of p53 vs. Cancer.
Zhang P, Christen SP, Bond GL. Zhang P, et al. J Mol Cell Biol. 2019 Jul 19;11(7):628-629. doi: 10.1093/jmcb/mjz078. J Mol Cell Biol. 2019. PMID: 31408158 Free PMC article. No abstract available.
A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence.
Surakhy M, Wallace M, Bond E, Grochola LF, Perez H, Di Giovannantonio M, Zhang P, Malkin D, Carter H, Parise IZS, Zambetti G, Komechen H, Paraizo MM, Pagadala MS, Pinto EM, Lalli E, Figueiredo BC, Bond GL. Surakhy M, et al. Among authors: zhang p. Br J Cancer. 2020 Apr;122(8):1231-1241. doi: 10.1038/s41416-020-0764-3. Epub 2020 Mar 9. Br J Cancer. 2020. PMID: 32147670 Free PMC article.
Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits.
Di Giovannantonio M, Harris BH, Zhang P, Kitchen-Smith I, Xiong L, Sahgal N, Stracquadanio G, Wallace M, Blagden S, Lord S, Harris D, Harris AHL, Buffa FM, Bond GL. Di Giovannantonio M, et al. Among authors: zhang p. J Med Genet. 2021 Jun;58(6):392-399. doi: 10.1136/jmedgenet-2019-106799. Epub 2020 Jun 26. J Med Genet. 2021. PMID: 32591342 Free PMC article.
Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer.
Wiecek AJ, Cutty SJ, Kornai D, Parreno-Centeno M, Gourmet LE, Tagliazucchi GM, Jacobson DH, Zhang P, Xiong L, Bond GL, Barr AR, Secrier M. Wiecek AJ, et al. Among authors: zhang p. Genome Biol. 2023 May 23;24(1):128. doi: 10.1186/s13059-023-02963-4. Genome Biol. 2023. PMID: 37221612 Free PMC article.
New role of fat-free mass in cancer risk linked with genetic predisposition.
Harris BHL, Di Giovannantonio M, Zhang P, Harris DA, Lord SR, Allen NE, Maughan TS, Bryant RJ, Harris AL, Bond GL, Buffa FM. Harris BHL, et al. Among authors: zhang p. Sci Rep. 2024 Mar 27;14(1):7270. doi: 10.1038/s41598-024-54291-7. Sci Rep. 2024. PMID: 38538606 Free PMC article.
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19.
Kotanidis CP, Xie C, Alexander D, Rodrigues JCL, Burnham K, Mentzer A, O'Connor D, Knight J, Siddique M, Lockstone H, Thomas S, Kotronias R, Oikonomou EK, Badi I, Lyasheva M, Shirodaria C, Lumley SF, Constantinides B, Sanderson N, Rodger G, Chau KK, Lodge A, Tsakok M, Gleeson F, Adlam D, Rao P, Indrajeet D, Deshpande A, Bajaj A, Hudson BJ, Srivastava V, Farid S, Krasopoulos G, Sayeed R, Ho LP, Neubauer S, Newby DE, Channon KM, Deanfield J, Antoniades C; COMBAT Consortium; ORFAN investigators. Kotanidis CP, et al. Lancet Digit Health. 2022 Oct;4(10):e705-e716. doi: 10.1016/S2589-7500(22)00132-7. Epub 2022 Aug 26. Lancet Digit Health. 2022. PMID: 36038496 Free PMC article.
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