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Pyruvate Kinase M2 Activates mTORC1 by Phosphorylating AKT1S1.
He CL, Bian YY, Xue Y, Liu ZX, Zhou KQ, Yao CF, Lin Y, Zou HF, Luo FX, Qu YY, Zhao JY, Ye ML, Zhao SM, Xu W. He CL, et al. Sci Rep. 2016 Feb 15;6:21524. doi: 10.1038/srep21524. Sci Rep. 2016. PMID: 26876154 Free PMC article.
Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer.
Jin X, Wang J, Gao K, Zhang P, Yao L, Tang Y, Tang L, Ma J, Xiao J, Zhang E, Zhu J, Zhang B, Zhao SM, Li Y, Ren S, Huang H, Yu L, Wang C. Jin X, et al. Among authors: zhao sm. PLoS Genet. 2017 Apr 27;13(4):e1006748. doi: 10.1371/journal.pgen.1006748. eCollection 2017 Apr. PLoS Genet. 2017. PMID: 28448495 Free PMC article.
Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.
Zhang P, Wang D, Zhao Y, Ren S, Gao K, Ye Z, Wang S, Pan CW, Zhu Y, Yan Y, Yang Y, Wu D, He Y, Zhang J, Lu D, Liu X, Yu L, Zhao S, Li Y, Lin D, Wang Y, Wang L, Chen Y, Sun Y, Wang C, Huang H. Zhang P, et al. Among authors: zhao y, zhao s. Nat Med. 2017 Sep;23(9):1055-1062. doi: 10.1038/nm.4379. Epub 2017 Aug 14. Nat Med. 2017. PMID: 28805822 Free PMC article.
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