Zhong X - Search Results

1

A "spindle and thread" mechanism unblocks p53 translation by modulating N-terminal disorder.

Kaldmäe M, Vosselman T, Zhong X, Lama D, Chen G, Saluri M, Kronqvist N, Siau JW, Ng AS, Ghadessy FJ, Sabatier P, Vojtesek B, Sarr M, Sahin C, Österlund N, Ilag LL, Väänänen VA, Sedimbi S, Arsenian-Henriksson M, Zubarev RA, Nilsson L, Koeck PJB, Rising A, Abelein A, Fritz N, Johansson J, Lane DP, Landreh M. Kaldmäe M, et al. Among authors: zhong x. Structure. 2022 May 5;30(5):733-742.e7. doi: 10.1016/j.str.2022.02.013. Epub 2022 Mar 14. Structure. 2022. PMID: 35290795 Free article.

2

Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro.

Chen G, Andrade-Talavera Y, Tambaro S, Leppert A, Nilsson HE, Zhong X, Landreh M, Nilsson P, Hebert H, Biverstål H, Fisahn A, Abelein A, Johansson J. Chen G, et al. Among authors: zhong x. Commun Biol. 2020 Jan 20;3(1):32. doi: 10.1038/s42003-020-0757-z. Commun Biol. 2020. PMID: 31959875 Free PMC article.

3

Recombinant Bri3 BRICHOS domain is a molecular chaperone with effect against amyloid formation and non-fibrillar protein aggregation.

Poska H, Leppert A, Tigro H, Zhong X, Kaldmäe M, Nilsson HE, Hebert H, Chen G, Johansson J. Poska H, et al. Among authors: zhong x. Sci Rep. 2020 Jun 17;10(1):9817. doi: 10.1038/s41598-020-66718-y. Sci Rep. 2020. PMID: 32555390 Free PMC article.

4

Molecular Chaperone BRICHOS Inhibits CADASIL-Mutated NOTCH3 Aggregation In Vitro.

Oliveira DV, Svensson J, Zhong X, Biverstål H, Chen G, Karlström H. Oliveira DV, et al. Among authors: zhong x. Front Mol Biosci. 2022 Feb 9;9:812808. doi: 10.3389/fmolb.2022.812808. eCollection 2022. Front Mol Biosci. 2022. PMID: 35223989 Free PMC article.

5

Amyloid Fibril Formation of Arctic Amyloid-β 1-42 Peptide is Efficiently Inhibited by the BRICHOS Domain.

Zhong X, Kumar R, Wang Y, Biverstål H, Ingeborg Jegerschöld C, J B Koeck P, Johansson J, Abelein A, Chen G. Zhong X, et al. ACS Chem Biol. 2022 Aug 19;17(8):2201-2211. doi: 10.1021/acschembio.2c00344. Epub 2022 Jul 25. ACS Chem Biol. 2022. PMID: 35876740 Free PMC article.

6

ATP-independent molecular chaperone activity generated under reducing conditions.

Leppert A, Chen G, Lianoudaki D, Williams C, Zhong X, Gilthorpe JD, Landreh M, Johansson J. Leppert A, et al. Among authors: zhong x. Protein Sci. 2022 Aug;31(8):e4378. doi: 10.1002/pro.4378. Protein Sci. 2022. PMID: 35900025 Free PMC article.

7

Abilities of the BRICHOS domain to prevent neurotoxicity and fibril formation are dependent on a highly conserved Asp residue.

Chen G, Andrade-Talavera Y, Zhong X, Hassan S, Biverstål H, Poska H, Abelein A, Leppert A, Kronqvist N, Rising A, Hebert H, Koeck PJB, Fisahn A, Johansson J. Chen G, et al. Among authors: zhong x. RSC Chem Biol. 2022 Sep 15;3(11):1342-1358. doi: 10.1039/d2cb00187j. eCollection 2022 Nov 2. RSC Chem Biol. 2022. PMID: 36349220 Free PMC article.

8

Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation.

Chen G, Leppert A, Poska H, Nilsson HE, Alvira CP, Zhong X, Koeck P, Jegerschöld C, Abelein A, Hebert H, Johansson J. Chen G, et al. Among authors: zhong x. Commun Biol. 2023 May 8;6(1):497. doi: 10.1038/s42003-023-04883-2. Commun Biol. 2023. PMID: 37156997 Free PMC article.

9

Spider Silk Protein Forms Amyloid-Like Nanofibrils through a Non-Nucleation-Dependent Polymerization Mechanism.

Qi X, Wang Y, Yu H, Liu R, Leppert A, Zheng Z, Zhong X, Jin Z, Wang H, Li X, Wang X, Landreh M, A Morozova-Roche L, Johansson J, Xiong S, Iashchishyn I, Chen G. Qi X, et al. Among authors: zhong x. Small. 2023 Nov;19(46):e2304031. doi: 10.1002/smll.202304031. Epub 2023 Jul 16. Small. 2023. PMID: 37455347

10

Label-free Single-Molecule Quantification of Rapamycin-induced FKBP-FRB Dimerization for Direct Control of Cellular Mechanotransduction.

Wang Y, Barnett SFH, Le S, Guo Z, Zhong X, Kanchanawong P, Yan J. Wang Y, et al. Among authors: zhong x. Nano Lett. 2019 Oct 9;19(10):7514-7525. doi: 10.1021/acs.nanolett.9b03364. Epub 2019 Sep 6. Nano Lett. 2019. PMID: 31466449

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