Zhou A - Search Results

1

Targeting a surface cavity of alpha 1-antitrypsin to prevent conformational disease.

Parfrey H, Mahadeva R, Ravenhill NA, Zhou A, Dafforn TR, Foreman RC, Lomas DA. Parfrey H, et al. Among authors: zhou a. J Biol Chem. 2003 Aug 29;278(35):33060-6. doi: 10.1074/jbc.M302646200. Epub 2003 Jun 13. J Biol Chem. 2003. PMID: 12807889 Free article.

2

Polymerization of plasminogen activator inhibitor-1.

Zhou A, Faint R, Charlton P, Dafforn TR, Carrell RW, Lomas DA. Zhou A, et al. J Biol Chem. 2001 Mar 23;276(12):9115-22. doi: 10.1074/jbc.M010631200. Epub 2000 Dec 1. J Biol Chem. 2001. PMID: 11102455 Free article.

3

How small peptides block and reverse serpin polymerisation.

Zhou A, Stein PE, Huntington JA, Sivasothy P, Lomas DA, Carrell RW. Zhou A, et al. J Mol Biol. 2004 Sep 17;342(3):931-41. doi: 10.1016/j.jmb.2004.07.078. J Mol Biol. 2004. PMID: 15342247

4

Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol.

Zhou A, Stein PE, Huntington JA, Carrell RW. Zhou A, et al. J Biol Chem. 2003 Apr 25;278(17):15116-22. doi: 10.1074/jbc.M211663200. Epub 2003 Feb 10. J Biol Chem. 2003. PMID: 12578831 Free article.

5

Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin.

Janciauskiene S, Eriksson S, Callea F, Mallya M, Zhou A, Seyama K, Hata S, Lomas DA. Janciauskiene S, et al. Among authors: zhou a. Hepatology. 2004 Nov;40(5):1203-10. doi: 10.1002/hep.20451. Hepatology. 2004. PMID: 15486938

6

Molecular Mechanism of Z α1-Antitrypsin Deficiency.

Huang X, Zheng Y, Zhang F, Wei Z, Wang Y, Carrell RW, Read RJ, Chen GQ, Zhou A. Huang X, et al. Among authors: zhou a. J Biol Chem. 2016 Jul 22;291(30):15674-86. doi: 10.1074/jbc.M116.727826. Epub 2016 May 31. J Biol Chem. 2016. PMID: 27246852 Free PMC article.

7

The serpin inhibitory mechanism is critically dependent on the length of the reactive center loop.

Zhou A, Carrell RW, Huntington JA. Zhou A, et al. J Biol Chem. 2001 Jul 20;276(29):27541-7. doi: 10.1074/jbc.M102594200. Epub 2001 Apr 26. J Biol Chem. 2001. PMID: 11325972 Free article.

8

Antithrombins Wibble and Wobble (T85M/K): archetypal conformational diseases with in vivo latent-transition, thrombosis, and heparin activation.

Beauchamp NJ, Pike RN, Daly M, Butler L, Makris M, Dafforn TR, Zhou A, Fitton HL, Preston FE, Peake IR, Carrell RW. Beauchamp NJ, et al. Among authors: zhou a. Blood. 1998 Oct 15;92(8):2696-706. Blood. 1998. PMID: 9763552 Free article.

9

Helix D elongation and allosteric activation of antithrombin.

Belzar KJ, Zhou A, Carrell RW, Gettins PG, Huntington JA. Belzar KJ, et al. Among authors: zhou a. J Biol Chem. 2002 Mar 8;277(10):8551-8. doi: 10.1074/jbc.M110807200. Epub 2001 Dec 10. J Biol Chem. 2002. PMID: 11741963 Free article.

10

Structural basis for the specificity of renin-mediated angiotensinogen cleavage.

Yan Y, Zhou A, Carrell RW, Read RJ. Yan Y, et al. Among authors: zhou a. J Biol Chem. 2019 Feb 15;294(7):2353-2364. doi: 10.1074/jbc.RA118.006608. Epub 2018 Dec 18. J Biol Chem. 2019. PMID: 30563843 Free PMC article.

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