Zhou XL - Search Results

1

Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease.

Zheng WQ, Pedersen SV, Thompson K, Bellacchio E, French CE, Munro B, Pearson TS, Vogt J, Diodato D, Diemer T, Ernst A, Horvath R, Chitre M, Ek J, Wibrand F, Grange DK, Raymond L, Zhou XL, Taylor RW, Ostergaard E. Zheng WQ, et al. Among authors: zhou xl. Hum Mol Genet. 2022 Feb 21;31(4):523-534. doi: 10.1093/hmg/ddab257. Hum Mol Genet. 2022. PMID: 34508595

2

A Human Disease-causing Point Mutation in Mitochondrial Threonyl-tRNA Synthetase Induces Both Structural and Functional Defects.

Wang Y, Zhou XL, Ruan ZR, Liu RJ, Eriani G, Wang ED. Wang Y, et al. Among authors: zhou xl. J Biol Chem. 2016 Mar 18;291(12):6507-20. doi: 10.1074/jbc.M115.700849. Epub 2016 Jan 25. J Biol Chem. 2016. PMID: 26811336 Free PMC article.

3

A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities.

Chen Y, Ruan ZR, Wang Y, Huang Q, Xue MQ, Zhou XL, Wang ED. Chen Y, et al. Among authors: zhou xl. Nucleic Acids Res. 2018 Apr 20;46(7):3643-3656. doi: 10.1093/nar/gky211. Nucleic Acids Res. 2018. PMID: 29579307 Free PMC article.

4

A natural non-Watson-Crick base pair in human mitochondrial tRNAThr causes structural and functional susceptibility to local mutations.

Wang Y, Zeng QY, Zheng WQ, Ji QQ, Zhou XL, Wang ED. Wang Y, et al. Among authors: zhou xl. Nucleic Acids Res. 2018 May 18;46(9):4662-4676. doi: 10.1093/nar/gky243. Nucleic Acids Res. 2018. PMID: 29648639 Free PMC article.

5

Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy.

Sommerville EW, Zhou XL, Oláhová M, Jenkins J, Euro L, Konovalova S, Hilander T, Pyle A, He L, Habeebu S, Saunders C, Kelsey A, Morris AAM, McFarland R, Suomalainen A, Gorman GS, Wang ED, Thiffault I, Tyynismaa H, Taylor RW. Sommerville EW, et al. Among authors: zhou xl. Hum Mol Genet. 2019 Jan 15;28(2):258-268. doi: 10.1093/hmg/ddy294. Hum Mol Genet. 2019. PMID: 30285085 Free PMC article.

6

The G3-U70-independent tRNA recognition by human mitochondrial alanyl-tRNA synthetase.

Zeng QY, Peng GX, Li G, Zhou JB, Zheng WQ, Xue MQ, Wang ED, Zhou XL. Zeng QY, et al. Among authors: zhou xl, zhou jb. Nucleic Acids Res. 2019 Apr 8;47(6):3072-3085. doi: 10.1093/nar/gkz078. Nucleic Acids Res. 2019. PMID: 30952159 Free PMC article.

7

Nitrosative stress inhibits aminoacylation and editing activities of mitochondrial threonyl-tRNA synthetase by S-nitrosation.

Zheng WQ, Zhang Y, Yao Q, Chen Y, Qiao X, Wang ED, Chen C, Zhou XL. Zheng WQ, et al. Among authors: zhou xl. Nucleic Acids Res. 2020 Jul 9;48(12):6799-6810. doi: 10.1093/nar/gkaa471. Nucleic Acids Res. 2020. PMID: 32484546 Free PMC article.

8

Selective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease.

Yu T, Zhang Y, Zheng WQ, Wu S, Li G, Zhang Y, Li N, Yao R, Fang P, Wang J, Zhou XL. Yu T, et al. Among authors: zhou xl. Nucleic Acids Res. 2022 Nov 11;50(20):11755-11774. doi: 10.1093/nar/gkac1028. Nucleic Acids Res. 2022. PMID: 36350636 Free PMC article.

9

Mammalian mitochondrial translation infidelity leads to oxidative stress-induced cell cycle arrest and cardiomyopathy.

Zheng WQ, Zhang JH, Li ZH, Liu X, Zhang Y, Huang S, Li J, Zhou B, Eriani G, Wang ED, Zhou XL. Zheng WQ, et al. Among authors: zhou xl, zhou b. Proc Natl Acad Sci U S A. 2023 Sep 12;120(37):e2309714120. doi: 10.1073/pnas.2309714120. Epub 2023 Sep 5. Proc Natl Acad Sci U S A. 2023. PMID: 37669377 Free PMC article.

10

Two tyrosine residues outside the editing active site in Giardia lamblia leucyl-tRNA synthetase are essential for the post-transfer editing.

Zhou XL, Wang ED. Zhou XL, et al. Biochem Biophys Res Commun. 2009 Aug 28;386(3):510-5. doi: 10.1016/j.bbrc.2009.06.070. Epub 2009 Jun 18. Biochem Biophys Res Commun. 2009. PMID: 19540202

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