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Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.
Nat Med. 2016 Dec;22(12):1402-1410. doi: 10.1038/nm.4200. Epub 2016 Oct 24.
Nat Med. 2016.
PMID: 27775706
Free PMC article.
Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.
Zhu EF, Gai SA, Opel CF, Kwan BH, Surana R, Mihm MC, Kauke MJ, Moynihan KD, Angelini A, Williams RT, Stephan MT, Kim JS, Yaffe MB, Irvine DJ, Weiner LM, Dranoff G, Wittrup KD.
Zhu EF, et al.
Cancer Cell. 2015 Apr 13;27(4):489-501. doi: 10.1016/j.ccell.2015.03.004.
Cancer Cell. 2015.
PMID: 25873172
Free PMC article.
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Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy.
Tzeng A, Kauke MJ, Zhu EF, Moynihan KD, Opel CF, Yang NJ, Mehta N, Kelly RL, Szeto GL, Overwijk WW, Irvine DJ, Wittrup KD.
Tzeng A, et al. Among authors: zhu ef.
Cell Rep. 2016 Dec 6;17(10):2503-2511. doi: 10.1016/j.celrep.2016.11.020.
Cell Rep. 2016.
PMID: 27926855
Free PMC article.
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Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses.
Kwan BH, Zhu EF, Tzeng A, Sugito HR, Eltahir AA, Ma B, Delaney MK, Murphy PA, Kauke MJ, Angelini A, Momin N, Mehta NK, Maragh AM, Hynes RO, Dranoff G, Cochran JR, Wittrup KD.
Kwan BH, et al. Among authors: zhu ef.
J Exp Med. 2017 Jun 5;214(6):1679-1690. doi: 10.1084/jem.20160831. Epub 2017 May 4.
J Exp Med. 2017.
PMID: 28473400
Free PMC article.
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Artificial Anti-Tumor Opsonizing Proteins with Fibronectin Scaffolds Engineered for Specificity to Each of the Murine FcγR Types.
Chen TF, Li KK, Zhu EF, Opel CF, Kauke MJ, Kim H, Atolia E, Wittrup KD.
Chen TF, et al. Among authors: zhu ef.
J Mol Biol. 2018 Jun 8;430(12):1786-1798. doi: 10.1016/j.jmb.2018.04.021. Epub 2018 Apr 25.
J Mol Biol. 2018.
PMID: 29704491
Free PMC article.
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Koch Institute Symposium on Cancer Immunology and Immunotherapy.
Drake A, Joshi NS, Szeto GL, Zhu E, Eisen HN, Irvine DJ.
Drake A, et al.
Cancer Immunol Res. 2013 Oct;1:217-222. doi: 10.1158/2326-6066.CIR-13-0116.
Cancer Immunol Res. 2013.
PMID: 24466562
Free PMC article.
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