Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective.
Qiu Z, Norflus F, Singh B, Swindell MK, Buzescu R, Bejarano M, Chopra R, Zucker B, Benn CL, DiRocco DP, Cha JH, Ferrante RJ, Hersch SM.
Qiu Z, et al. Among authors: zucker b.
J Biol Chem. 2006 Jun 16;281(24):16672-80. doi: 10.1074/jbc.M511648200. Epub 2006 Apr 4.
J Biol Chem. 2006.
PMID: 16595660
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