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Glutamine synthetase licenses APC/C-mediated mitotic progression to drive cell growth.
Zhao JS, Shi S, Qu HY, Keckesova Z, Cao ZJ, Yang LX, Yu X, Feng L, Shi Z, Krakowiak J, Mao RY, Shen YT, Fan YM, Fu TM, Ye C, Xu D, Gao X, You J, Li W, Liang T, Lu Z, Feng YX. Zhao JS, et al. Among authors: keckesova z. Nat Metab. 2022 Feb;4(2):239-253. doi: 10.1038/s42255-021-00524-2. Epub 2022 Feb 10. Nat Metab. 2022. PMID: 35145325
LACTB is a tumour suppressor that modulates lipid metabolism and cell state.
Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA. Keckesova Z, et al. Nature. 2017 Mar 30;543(7647):681-686. doi: 10.1038/nature21408. Epub 2017 Mar 22. Nature. 2017. PMID: 28329758 Free PMC article.
LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug.
Cutano V, Ferreira Mendes JM, Escudeiro-Lopes S, Machado S, Vinaixa Forner J, Gonzales-Morena JM, Prevorovsky M, Zemlianski V, Feng Y, Kralova Viziova P, Hartmanova A, Malcekova B, Jakoube P, Iyer S, Keckesova Z. Cutano V, et al. Among authors: keckesova z. Life Sci Alliance. 2022 Nov 14;6(1):e202201510. doi: 10.26508/lsa.202201510. Print 2023 Jan. Life Sci Alliance. 2022. PMID: 36375842 Free PMC article.
Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency.
De Cock JM, Shibue T, Dongre A, Keckesova Z, Reinhardt F, Weinberg RA. De Cock JM, et al. Among authors: keckesova z. Cancer Res. 2016 Dec 1;76(23):6778-6784. doi: 10.1158/0008-5472.CAN-16-0608. Epub 2016 Aug 16. Cancer Res. 2016. PMID: 27530323 Free PMC article.
LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer.
Gonzalez-Morena JM, Escudeiro-Lopes S, Ferreira-Mendes JM, Jakoube P, Cutano V, Vinaixa-Forner J, Kralova Viziova P, Hartmanova A, Sedlacek R, Machado S, Malcekova B, Keckesova Z. Gonzalez-Morena JM, et al. Among authors: keckesova z. Apoptosis. 2023 Feb;28(1-2):186-198. doi: 10.1007/s10495-022-01775-4. Epub 2022 Oct 25. Apoptosis. 2023. PMID: 36282364 Free PMC article.
Correction: LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug.
Cutano V, Ferreira Mendes JM, Escudeiro-Lopes S, Machado S, Vinaixa Forner J, Gonzales-Morena JM, Prevorovsky M, Zemlianski V, Feng Y, Kralova Viziova P, Hartmanova A, Malcekova B, Jakoube P, Iyer S, Keckesova Z. Cutano V, et al. Among authors: keckesova z. Life Sci Alliance. 2023 Dec 6;7(2):e202302497. doi: 10.26508/lsa.202302497. Print 2024 Feb. Life Sci Alliance. 2023. PMID: 38056910 Free PMC article.
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