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Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1.
Janssen B, Hohenadel D, Brinkkoetter P, Peters V, Rind N, Fischer C, Rychlik I, Cerna M, Romzova M, de Heer E, Baelde H, Bakker SJ, Zirie M, Rondeau E, Mathieson P, Saleem MA, Meyer J, Köppel H, Sauerhoefer S, Bartram CR, Nawroth P, Hammes HP, Yard BA, Zschocke J, van der Woude FJ. Janssen B, et al. Among authors: de heer e. Diabetes. 2005 Aug;54(8):2320-7. doi: 10.2337/diabetes.54.8.2320. Diabetes. 2005. PMID: 16046297
Association between CNDP1 genotype and diabetic nephropathy is sex specific.
Mooyaart AL, Zutinic A, Bakker SJ, Grootendorst DC, Kleefstra N, van Valkengoed IG, Böhringer S, Bilo HJ, Dekker FW, Bruijn JA, Navis G, Janssen B, Baelde HJ, De Heer E. Mooyaart AL, et al. Among authors: de heer e. Diabetes. 2010 Jun;59(6):1555-9. doi: 10.2337/db09-1377. Epub 2010 Mar 23. Diabetes. 2010. PMID: 20332346 Free PMC article.
Intrinsic carnosine metabolism in the human kidney.
Peters V, Klessens CQ, Baelde HJ, Singler B, Veraar KA, Zutinic A, Drozak J, Zschocke J, Schmitt CP, de Heer E. Peters V, et al. Among authors: de heer e. Amino Acids. 2015 Dec;47(12):2541-50. doi: 10.1007/s00726-015-2045-7. Epub 2015 Jul 24. Amino Acids. 2015. PMID: 26206726 Free PMC article.
Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice.
Albrecht T, Schilperoort M, Zhang S, Braun JD, Qiu J, Rodriguez A, Pastene DO, Krämer BK, Köppel H, Baelde H, de Heer E, Anna Altomare A, Regazzoni L, Denisi A, Aldini G, van den Born J, Yard BA, Hauske SJ. Albrecht T, et al. Among authors: de heer e. Sci Rep. 2017 Mar 10;7:44492. doi: 10.1038/srep44492. Sci Rep. 2017. PMID: 28281693 Free PMC article.
Lower frequency of the 5/5 homozygous CNDP1 genotype in South Asian Surinamese.
Mooyaart AL, van Valkengoed IG, Shaw PK, Peters V, Baelde HJ, Rabelink TJ, Bruijn JA, Stronks K, de Heer E. Mooyaart AL, et al. Among authors: de heer e. Diabetes Res Clin Pract. 2009 Sep;85(3):272-8. doi: 10.1016/j.diabres.2009.06.001. Epub 2009 Jul 3. Diabetes Res Clin Pract. 2009. PMID: 19577318
Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humans.
Everaert I, Taes Y, De Heer E, Baelde H, Zutinic A, Yard B, Sauerhöfer S, Vanhee L, Delanghe J, Aldini G, Derave W. Everaert I, et al. Among authors: de heer e. Am J Physiol Renal Physiol. 2012 Jun 15;302(12):F1537-44. doi: 10.1152/ajprenal.00084.2012. Epub 2012 Apr 11. Am J Physiol Renal Physiol. 2012. PMID: 22496410 Free article.
Does low serum carnosinase activity favor high-intensity exercise capacity?
Baguet A, Everaert I, Yard B, Peters V, Zschocke J, Zutinic A, De Heer E, Podgórski T, Domaszewska K, Derave W. Baguet A, et al. Among authors: de heer e. J Appl Physiol (1985). 2014 Mar 1;116(5):553-9. doi: 10.1152/japplphysiol.01218.2013. Epub 2014 Jan 9. J Appl Physiol (1985). 2014. PMID: 24408989 Free article. Clinical Trial.
243 results