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eRNAs are required for p53-dependent enhancer activity and gene transcription.
Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. Melo CA, et al. Among authors: de laat w, de wit e. Mol Cell. 2013 Feb 7;49(3):524-35. doi: 10.1016/j.molcel.2012.11.021. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273978 Free article.
Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells.
Holwerda SJ, van de Werken HJ, Ribeiro de Almeida C, Bergen IM, de Bruijn MJ, Verstegen MJ, Simonis M, Splinter E, Wijchers PJ, Hendriks RW, de Laat W. Holwerda SJ, et al. Among authors: de bruijn mj, de laat w. Nucleic Acids Res. 2013 Aug;41(14):6905-16. doi: 10.1093/nar/gkt491. Epub 2013 Jun 7. Nucleic Acids Res. 2013. PMID: 23748562 Free PMC article.
A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia.
Gröschel S, Sanders MA, Hoogenboezem R, de Wit E, Bouwman BAM, Erpelinck C, van der Velden VHJ, Havermans M, Avellino R, van Lom K, Rombouts EJ, van Duin M, Döhner K, Beverloo HB, Bradner JE, Döhner H, Löwenberg B, Valk PJM, Bindels EMJ, de Laat W, Delwel R. Gröschel S, et al. Among authors: de laat w, de wit e. Cell. 2014 Apr 10;157(2):369-381. doi: 10.1016/j.cell.2014.02.019. Epub 2014 Apr 3. Cell. 2014. PMID: 24703711 Free article.
Large-scale identification of coregulated enhancer networks in the adult human brain.
Vermunt MW, Reinink P, Korving J, de Bruijn E, Creyghton PM, Basak O, Geeven G, Toonen PW, Lansu N, Meunier C, van Heesch S; Netherlands Brain Bank; Clevers H, de Laat W, Cuppen E, Creyghton MP. Vermunt MW, et al. Among authors: de laat w, de bruijn e. Cell Rep. 2014 Oct 23;9(2):767-79. doi: 10.1016/j.celrep.2014.09.023. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373911 Free article.
Characterization and dynamics of pericentromere-associated domains in mice.
Wijchers PJ, Geeven G, Eyres M, Bergsma AJ, Janssen M, Verstegen M, Zhu Y, Schell Y, Vermeulen C, de Wit E, de Laat W. Wijchers PJ, et al. Among authors: de laat w, de wit e. Genome Res. 2015 Jul;25(7):958-69. doi: 10.1101/gr.186643.114. Epub 2015 Apr 16. Genome Res. 2015. PMID: 25883320 Free PMC article.
A Long-Distance Chromatin Affair.
Denker A, de Laat W. Denker A, et al. Among authors: de laat w. Cell. 2015 Aug 27;162(5):942-3. doi: 10.1016/j.cell.2015.08.022. Cell. 2015. PMID: 26317462 Free article.
140 results