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Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein.
Mastrangelo E, Milani M, Bollati M, Selisko B, Peyrane F, Pandini V, Sorrentino G, Canard B, Konarev PV, Svergun DI, de Lamballerie X, Coutard B, Khromykh AA, Bolognesi M. Mastrangelo E, et al. Among authors: de lamballerie x. J Mol Biol. 2007 Sep 14;372(2):444-55. doi: 10.1016/j.jmb.2007.06.055. Epub 2007 Jun 27. J Mol Biol. 2007. PMID: 17658551 Free article.
Crystal structure of a methyltransferase from a no-known-vector Flavivirus.
Bollati M, Milani M, Mastrangelo E, de Lamballerie X, Canard B, Bolognesi M. Bollati M, et al. Among authors: de lamballerie x. Biochem Biophys Res Commun. 2009 Apr 24;382(1):200-4. doi: 10.1016/j.bbrc.2009.03.008. Epub 2009 Mar 9. Biochem Biophys Res Commun. 2009. PMID: 19275894
Preliminary crystallographic characterization of an RNA helicase from Kunjin virus.
Mastrangelo E, Bollati M, Milani M, Brisbarre N, de Lamballerie X, Coutard B, Canard B, Khromykh A, Bolognesi M. Mastrangelo E, et al. Among authors: de lamballerie x. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt 9):876-9. doi: 10.1107/S1744309106028776. Epub 2006 Aug 11. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16946468 Free PMC article.
Structure and functionality in flavivirus NS-proteins: perspectives for drug design.
Bollati M, Alvarez K, Assenberg R, Baronti C, Canard B, Cook S, Coutard B, Decroly E, de Lamballerie X, Gould EA, Grard G, Grimes JM, Hilgenfeld R, Jansson AM, Malet H, Mancini EJ, Mastrangelo E, Mattevi A, Milani M, Moureau G, Neyts J, Owens RJ, Ren J, Selisko B, Speroni S, Steuber H, Stuart DI, Unge T, Bolognesi M. Bollati M, et al. Among authors: de lamballerie x. Antiviral Res. 2010 Aug;87(2):125-48. doi: 10.1016/j.antiviral.2009.11.009. Epub 2009 Nov 27. Antiviral Res. 2010. PMID: 19945487 Free PMC article. Review.
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug.
Mastrangelo E, Pezzullo M, De Burghgraeve T, Kaptein S, Pastorino B, Dallmeier K, de Lamballerie X, Neyts J, Hanson AM, Frick DN, Bolognesi M, Milani M. Mastrangelo E, et al. Among authors: de burghgraeve t, de lamballerie x. J Antimicrob Chemother. 2012 Aug;67(8):1884-94. doi: 10.1093/jac/dks147. Epub 2012 Apr 25. J Antimicrob Chemother. 2012. PMID: 22535622 Free PMC article.
Preliminary characterization of (nucleoside-2'-O-)-methyltransferase crystals from Meaban and Yokose flaviviruses.
Mastrangelo E, Bollati M, Milani M, de Lamballerie X, Brisbarre N, Dalle K, Lantez V, Egloff MP, Coutard B, Canard B, Gould E, Forrester N, Bolognesi M. Mastrangelo E, et al. Among authors: de lamballerie x. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Aug 1;62(Pt 8):768-70. doi: 10.1107/S1744309106025553. Epub 2006 Jul 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16880552 Free PMC article.
Picornavirus non-structural proteins as targets for new anti-virals with broad activity.
Norder H, De Palma AM, Selisko B, Costenaro L, Papageorgiou N, Arnan C, Coutard B, Lantez V, De Lamballerie X, Baronti C, Solà M, Tan J, Neyts J, Canard B, Coll M, Gorbalenya AE, Hilgenfeld R. Norder H, et al. Among authors: de palma am, de lamballerie x. Antiviral Res. 2011 Mar;89(3):204-18. doi: 10.1016/j.antiviral.2010.12.007. Epub 2011 Jan 12. Antiviral Res. 2011. PMID: 21236302 Review.
The 2C putative helicase of echovirus 30 adopts a hexameric ring-shaped structure.
Papageorgiou N, Coutard B, Lantez V, Gautron E, Chauvet O, Baronti C, Norder H, de Lamballerie X, Heresanu V, Ferté N, Veesler S, Gorbalenya AE, Canard B. Papageorgiou N, et al. Among authors: de lamballerie x. Acta Crystallogr D Biol Crystallogr. 2010 Oct;66(Pt 10):1116-20. doi: 10.1107/S090744491002809X. Epub 2010 Sep 18. Acta Crystallogr D Biol Crystallogr. 2010. PMID: 20944244
628 results