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Antagonistic properties are shifted back to agonistic properties by further N-terminal shortening of pituitary adenylate-cyclase-activating peptides in human neuroblastoma NB-OK-1 cell membranes.
Vandermeers A, Vandenborre S, Hou X, de Neef P, Robberecht P, Vandermeers-Piret MC, Christophe J. Vandermeers A, et al. Among authors: de neef p. Eur J Biochem. 1992 Sep 15;208(3):815-9. doi: 10.1111/j.1432-1033.1992.tb17252.x. Eur J Biochem. 1992. PMID: 1327769 Free article.
Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes. Discovery of PACAP(6-38) as a potent antagonist.
Robberecht P, Gourlet P, De Neef P, Woussen-Colle MC, Vandermeers-Piret MC, Vandermeers A, Christophe J. Robberecht P, et al. Among authors: de neef p. Eur J Biochem. 1992 Jul 1;207(1):239-46. doi: 10.1111/j.1432-1033.1992.tb17043.x. Eur J Biochem. 1992. PMID: 1321043 Free article.
Receptor occupancy and adenylate cyclase activation in AR 4-2J rat pancreatic acinar cell membranes by analogs of pituitary adenylate cyclase-activating peptides amino-terminally shortened or modified at position 1, 2, 3, 20, or 21.
Robberecht P, Gourlet P, De Neef P, Woussen-Colle MC, Vandermeers-Piret MC, Vandermeers A, Christophe J. Robberecht P, et al. Among authors: de neef p. Mol Pharmacol. 1992 Aug;42(2):347-55. Mol Pharmacol. 1992. PMID: 1325033
The two forms of the pituitary adenylate cyclase activating polypeptide (PACAP (1-27) and PACAP (1-38)) interact with distinct receptors on rat pancreatic AR 4-2J cell membranes.
Robberecht P, Woussen-Colle MC, De Neef P, Gourlet P, Buscail L, Vandermeers A, Vandermeers-Piret MC, Christophe J. Robberecht P, et al. Among authors: de neef p. FEBS Lett. 1991 Jul 29;286(1-2):133-6. doi: 10.1016/0014-5793(91)80958-6. FEBS Lett. 1991. PMID: 1650711 Free article.
PACAP and VIP receptors in rat liver membranes.
Robberecht P, Gourlet P, Cauvin A, Buscail L, De Neef P, Arimura A, Christophe J. Robberecht P, et al. Among authors: de neef p. Am J Physiol. 1991 Jan;260(1 Pt 1):G97-102. doi: 10.1152/ajpgi.1991.260.1.G97. Am J Physiol. 1991. PMID: 1846275
Structural requirements for the binding of the pituitary adenylate-cyclase-activating peptide to receptors and adenylate-cyclase activation in pancreatic and neuronal membranes.
Gourlet P, Woussen-Colle MC, Robberecht P, de Neef P, Cauvin A, Vandermeers-Piret MC, Vandermeers A, Christophe J. Gourlet P, et al. Among authors: de neef p. Eur J Biochem. 1991 Jan 30;195(2):535-41. doi: 10.1111/j.1432-1033.1991.tb15734.x. Eur J Biochem. 1991. PMID: 1997328 Free article.
154 results