de Waart DR - Search Results

1

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.

Slijepcevic D, Roscam Abbing RLP, Katafuchi T, Blank A, Donkers JM, van Hoppe S, de Waart DR, Tolenaars D, van der Meer JHM, Wildenberg M, Beuers U, Oude Elferink RPJ, Schinkel AH, van de Graaf SFJ. Slijepcevic D, et al. Among authors: de waart dr. Hepatology. 2017 Nov;66(5):1631-1643. doi: 10.1002/hep.29251. Epub 2017 Sep 29. Hepatology. 2017. PMID: 28498614 Free PMC article.

2

Lack of UGT1 isoforms in Gunn rats changes metabolic ratio and facilitates excretion of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo.

Dietrich CG, Ottenhoff R, de Waart DR, Oude-Elferink RP. Dietrich CG, et al. Among authors: de waart dr. Toxicol Appl Pharmacol. 2001 Jan 15;170(2):137-43. doi: 10.1006/taap.2000.9090. Toxicol Appl Pharmacol. 2001. PMID: 11162778

3

Role of MRP2 and GSH in intrahepatic cycling of toxins.

Dietrich CG, Ottenhoff R, de Waart DR, Oude Elferink RP. Dietrich CG, et al. Among authors: de waart dr. Toxicology. 2001 Oct 5;167(1):73-81. doi: 10.1016/s0300-483x(01)00459-0. Toxicology. 2001. PMID: 11557131

4

Multidrug resistance associated protein 2 mediates transport of prostaglandin E2.

de Waart DR, Paulusma CC, Kunne C, Oude Elferink RP. de Waart DR, et al. Liver Int. 2006 Apr;26(3):362-8. doi: 10.1111/j.1478-3231.2005.01234.x. Liver Int. 2006. PMID: 16584400

5

Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.

Vlaming ML, Mohrmann K, Wagenaar E, de Waart DR, Elferink RP, Lagas JS, van Tellingen O, Vainchtein LD, Rosing H, Beijnen JH, Schellens JH, Schinkel AH. Vlaming ML, et al. Among authors: de waart dr. J Pharmacol Exp Ther. 2006 Jul;318(1):319-27. doi: 10.1124/jpet.106.101774. Epub 2006 Apr 12. J Pharmacol Exp Ther. 2006. PMID: 16611851 Free article.

6

ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity.

Paulusma CC, Folmer DE, Ho-Mok KS, de Waart DR, Hilarius PM, Verhoeven AJ, Oude Elferink RP. Paulusma CC, et al. Among authors: de waart dr. Hepatology. 2008 Jan;47(1):268-78. doi: 10.1002/hep.21950. Hepatology. 2008. PMID: 17948906

7

Evaluation of a new immortalized human fetal liver cell line (cBAL111) for application in bioartificial liver.

Poyck PP, van Wijk AC, van der Hoeven TV, de Waart DR, Chamuleau RA, van Gulik TM, Oude Elferink RP, Hoekstra R. Poyck PP, et al. Among authors: de waart dr. J Hepatol. 2008 Feb;48(2):266-75. doi: 10.1016/j.jhep.2007.09.018. Epub 2007 Dec 17. J Hepatol. 2008. PMID: 18093687

8

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, van Tellingen O, de Waart DR, Oude Elferink RP, van de Wetering K, Schinkel AH. Vlaming ML, et al. Among authors: de waart dr. Clin Cancer Res. 2008 Dec 15;14(24):8152-60. doi: 10.1158/1078-0432.CCR-08-1609. Clin Cancer Res. 2008. PMID: 19088030

9

Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo.

Vlaming ML, Pala Z, van Esch A, Wagenaar E, de Waart DR, van de Wetering K, van der Kruijssen CM, Oude Elferink RP, van Tellingen O, Schinkel AH. Vlaming ML, et al. Among authors: de waart dr. Clin Cancer Res. 2009 May 1;15(9):3084-93. doi: 10.1158/1078-0432.CCR-08-2940. Epub 2009 Apr 21. Clin Cancer Res. 2009. PMID: 19383815

10

Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

de Waart DR, Vlaming ML, Kunne C, Schinkel AH, Oude Elferink RP. de Waart DR, et al. Drug Metab Dispos. 2009 Aug;37(8):1698-702. doi: 10.1124/dmd.108.026146. Epub 2009 May 14. Drug Metab Dispos. 2009. PMID: 19443695

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