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A Restricted Role for FcγR in the Regulation of Adaptive Immunity.
Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS. Fransen MF, et al. Among authors: van harmelen v, van der kaa j, van kooten c, van beek l, van hall t, van maren ww, van heiningen s. J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9. J Immunol. 2018. PMID: 29523656 Free PMC article.
FcRγ-chain deficiency reduces the development of diet-induced obesity.
van Beek L, Vroegrijk IO, Katiraei S, Heemskerk MM, van Dam AD, Kooijman S, Rensen PC, Koning F, Verbeek JS, Willems van Dijk K, van Harmelen V. van Beek L, et al. Among authors: van harmelen v, van dam ad. Obesity (Silver Spring). 2015 Dec;23(12):2435-44. doi: 10.1002/oby.21309. Epub 2015 Nov 2. Obesity (Silver Spring). 2015. PMID: 26523352 Free article.
IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.
van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, Koning F, van Kooten C, Rensen PCN, Boon MR, Verbeek JS, van Dijk KW, van Harmelen V. van Dam AD, et al. Among authors: van harmelen v, van den bossche j, van kooten c, van dijk kw, van beek l, van den berg sm. Int J Obes (Lond). 2018 Feb;42(2):260-269. doi: 10.1038/ijo.2017.209. Epub 2017 Aug 30. Int J Obes (Lond). 2018. PMID: 28852207
The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice.
van Beek L, van Klinken JB, Pronk AC, van Dam AD, Dirven E, Rensen PC, Koning F, Willems van Dijk K, van Harmelen V. van Beek L, et al. Among authors: van harmelen v, van klinken jb, van dam ad. Diabetologia. 2015 Jul;58(7):1601-9. doi: 10.1007/s00125-015-3594-8. Epub 2015 May 12. Diabetologia. 2015. PMID: 25962520 Free PMC article.
Splenic autonomic denervation increases inflammatory status but does not aggravate atherosclerotic lesion development.
Kooijman S, Meurs I, van Beek L, Khedoe PP, Giezekamp A, Pike-Overzet K, Cailotto C, van der Vliet J, van Harmelen V, Boeckxstaens G, Berbée JF, Rensen PC. Kooijman S, et al. Among authors: van harmelen v, van beek l, van der vliet j. Am J Physiol Heart Circ Physiol. 2015 Aug 15;309(4):H646-54. doi: 10.1152/ajpheart.00787.2014. Epub 2015 Jun 19. Am J Physiol Heart Circ Physiol. 2015. PMID: 26092978 Free article.
Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice.
Hussaarts L, García-Tardón N, van Beek L, Heemskerk MM, Haeberlein S, van der Zon GC, Ozir-Fazalalikhan A, Berbée JF, Willems van Dijk K, van Harmelen V, Yazdanbakhsh M, Guigas B. Hussaarts L, et al. Among authors: van harmelen v, van beek l, van der zon gc. FASEB J. 2015 Jul;29(7):3027-39. doi: 10.1096/fj.14-266239. Epub 2015 Apr 7. FASEB J. 2015. PMID: 25852044
BMT decreases HFD-induced weight gain associated with decreased preadipocyte number and insulin secretion.
Katiraei S, Hoving LR, van Beek L, Mohamedhoesein S, Carlotti F, van Diepen JA, Rensen PCN, Netea MG, Willems van Dijk K, Berbée JFP, van Harmelen V. Katiraei S, et al. Among authors: van harmelen v, van diepen ja, van beek l. PLoS One. 2017 Apr 26;12(4):e0175524. doi: 10.1371/journal.pone.0175524. eCollection 2017. PLoS One. 2017. PMID: 28445487 Free PMC article.
Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.
van den Heuvel JK, Boon MR, van Hengel I, Peschier-van der Put E, van Beek L, van Harmelen V, van Dijk KW, Pereira AM, Hunt H, Belanoff JK, Rensen PC, Meijer OC. van den Heuvel JK, et al. Among authors: van harmelen v, van hengel i, van dijk kw, van beek l. Br J Pharmacol. 2016 Jun;173(11):1793-804. doi: 10.1111/bph.13477. Epub 2016 Apr 24. Br J Pharmacol. 2016. PMID: 26990179 Free PMC article.
56 results