van Heel DA - Search Results

1

Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo.

Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, Ryffel B, Quesniaux VF, Evans TW, Thiemermann C, Mitchell JA. Cartwright N, et al. Among authors: van heel da. Am J Respir Crit Care Med. 2007 Mar 15;175(6):595-603. doi: 10.1164/rccm.200608-1103OC. Epub 2007 Jan 18. Am J Respir Crit Care Med. 2007. PMID: 17234906

2

Synergistic enhancement of Toll-like receptor responses by NOD1 activation.

van Heel DA, Ghosh S, Butler M, Hunt K, Foxwell BM, Mengin-Lecreulx D, Playford RJ. van Heel DA, et al. Eur J Immunol. 2005 Aug;35(8):2471-6. doi: 10.1002/eji.200526296. Eur J Immunol. 2005. PMID: 16021603 Free article.

3

Normal responses to specific NOD1-activating peptidoglycan agonists in the presence of the NOD2 frameshift and other mutations in Crohn's disease.

van Heel DA, Hunt KA, Ghosh S, Hervé M, Playford RJ. van Heel DA, et al. Eur J Immunol. 2006 Jun;36(6):1629-35. doi: 10.1002/eji.200535636. Eur J Immunol. 2006. PMID: 16637007 Free article.

4

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease.

van Heel DA, Ghosh S, Butler M, Hunt KA, Lundberg AM, Ahmad T, McGovern DP, Onnie C, Negoro K, Goldthorpe S, Foxwell BM, Mathew CG, Forbes A, Jewell DP, Playford RJ. van Heel DA, et al. Lancet. 2005 May 21-27;365(9473):1794-6. doi: 10.1016/S0140-6736(05)66582-8. Lancet. 2005. PMID: 15910952

5

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease.

van Heel DA, Ghosh S, Hunt KA, Mathew CG, Forbes A, Jewell DP, Playford RJ. van Heel DA, et al. Gut. 2005 Nov;54(11):1553-7. doi: 10.1136/gut.2005.065888. Epub 2005 May 31. Gut. 2005. PMID: 15928043 Free PMC article.

6

Detection of muramyl dipeptide-sensing pathway defects in patients with Crohn's disease.

van Heel DA, Hunt KA, King K, Ghosh S, Gabe SM, Mathew CG, Forbes A, Playford RJ. van Heel DA, et al. Inflamm Bowel Dis. 2006 Jul;12(7):598-605. doi: 10.1097/01.ibd.0000225344.21979.89. Inflamm Bowel Dis. 2006. PMID: 16804397

7

Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays.

Franke L, de Kovel CG, Aulchenko YS, Trynka G, Zhernakova A, Hunt KA, Blauw HM, van den Berg LH, Ophoff R, Deloukas P, van Heel DA, Wijmenga C. Franke L, et al. Among authors: van heel da, van den berg lh. Am J Hum Genet. 2008 Jun;82(6):1316-33. doi: 10.1016/j.ajhg.2008.05.008. Am J Hum Genet. 2008. PMID: 18519066 Free PMC article.

8

Multiple common variants for celiac disease influencing immune gene expression.

Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek WH, Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA. Dubois PC, et al. Among authors: van heel da, van den berg lh. Nat Genet. 2010 Apr;42(4):295-302. doi: 10.1038/ng.543. Epub 2010 Feb 28. Nat Genet. 2010. PMID: 20190752 Free PMC article.

9

NOD2 activity modulates the phenotype of LPS-stimulated dendritic cells to promote the development of T-helper type 2-like lymphocytes - Possible implications for NOD2-associated Crohn's disease.

Butler M, Chaudhary R, van Heel DA, Playford RJ, Ghosh S. Butler M, et al. Among authors: van heel da. J Crohns Colitis. 2007 Dec;1(2):106-15. doi: 10.1016/j.crohns.2007.08.006. Epub 2007 Sep 27. J Crohns Colitis. 2007. PMID: 21172192

10

Health and population effects of rare gene knockouts in adult humans with related parents.

Narasimhan VM, Hunt KA, Mason D, Baker CL, Karczewski KJ, Barnes MR, Barnett AH, Bates C, Bellary S, Bockett NA, Giorda K, Griffiths CJ, Hemingway H, Jia Z, Kelly MA, Khawaja HA, Lek M, McCarthy S, McEachan R, O'Donnell-Luria A, Paigen K, Parisinos CA, Sheridan E, Southgate L, Tee L, Thomas M, Xue Y, Schnall-Levin M, Petkov PM, Tyler-Smith C, Maher ER, Trembath RC, MacArthur DG, Wright J, Durbin R, van Heel DA. Narasimhan VM, et al. Among authors: van heel da. Science. 2016 Apr 22;352(6284):474-7. doi: 10.1126/science.aac8624. Epub 2016 Mar 3. Science. 2016. PMID: 26940866 Free PMC article.

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