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Patient-Specific TBX5-G125R Variant Induces Profound Transcriptional Deregulation and Atrial Dysfunction.
van Ouwerkerk AF, Bosada FM, van Duijvenboden K, Houweling AC, Scholman KT, Wakker V, Allaart CP, Uhm JS, Mathijssen IB, Baartscheer T, Postma AV, Barnett P, Verkerk AO, Boukens BJ, Christoffels VM. van Ouwerkerk AF, et al. Circulation. 2022 Feb 22;145(8):606-619. doi: 10.1161/CIRCULATIONAHA.121.054347. Epub 2022 Feb 3. Circulation. 2022. PMID: 35113653 Free PMC article.
Identification of Functional Variant Enhancers Associated With Atrial Fibrillation.
van Ouwerkerk AF, Bosada FM, Liu J, Zhang J, van Duijvenboden K, Chaffin M, Tucker NR, Pijnappels D, Ellinor PT, Barnett P, de Vries AAF, Christoffels VM. van Ouwerkerk AF, et al. Circ Res. 2020 Jul 3;127(2):229-243. doi: 10.1161/CIRCRESAHA.119.316006. Epub 2020 Apr 6. Circ Res. 2020. PMID: 32248749 Free article.
Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation.
van Ouwerkerk AF, Hall AW, Kadow ZA, Lazarevic S, Reyat JS, Tucker NR, Nadadur RD, Bosada FM, Bianchi V, Ellinor PT, Fabritz L, Martin JF, de Laat W, Kirchhof P, Moskowitz IP, Christoffels VM. van Ouwerkerk AF, et al. Circ Res. 2020 Jun 19;127(1):34-50. doi: 10.1161/CIRCRESAHA.120.316574. Epub 2020 Jun 18. Circ Res. 2020. PMID: 32717170 Free PMC article. Review.
Identification of atrial fibrillation associated genes and functional non-coding variants.
van Ouwerkerk AF, Bosada FM, van Duijvenboden K, Hill MC, Montefiori LE, Scholman KT, Liu J, de Vries AAF, Boukens BJ, Ellinor PT, Goumans MJTH, Efimov IR, Nobrega MA, Barnett P, Martin JF, Christoffels VM. van Ouwerkerk AF, et al. Nat Commun. 2019 Oct 18;10(1):4755. doi: 10.1038/s41467-019-12721-5. Nat Commun. 2019. PMID: 31628324 Free PMC article.