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Hyperlipidaemia elicits an atypical, T helper 1-like CD4+ T-cell response: a key role for very low-density lipoprotein.
van Os BW, Vos WG, Bosmans LA, van Tiel CM, Lith SC, den Toom MS, Beckers L, Levels JHM, van Wouw SAE, Zelcer N, Zaal EA, Berkers CR, van der Lest CHA, Helms JB, Weber C, Atzler D, de Winther MPJ, Baardman J, Lutgens E. van Os BW, et al. Among authors: van wouw sae. Eur Heart J Open. 2023 Mar 3;3(2):oead013. doi: 10.1093/ehjopen/oead013. eCollection 2023 Mar. Eur Heart J Open. 2023. PMID: 36969380 Free PMC article.
Sterol-regulated transmembrane protein TMEM86a couples LXR signaling to regulation of lysoplasmalogens in macrophages.
van Wouw SAE, van den Berg M, El Ouraoui M, Meurs A, Kingma J, Ottenhoff R, Loix M, Hoeksema MA, Prange K, Pasterkamp G, Hendriks JJA, Bogie JFJ, van Klinken JB, Vaz FM, Jongejan A, de Winther MPJ, Zelcer N. van Wouw SAE, et al. J Lipid Res. 2023 Feb;64(2):100325. doi: 10.1016/j.jlr.2022.100325. Epub 2022 Dec 31. J Lipid Res. 2023. PMID: 36592658 Free PMC article.
DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.
Willemsen L, Prange KHM, Neele AE, van Roomen CPAA, Gijbels M, Griffith GR, Toom MD, Beckers L, Siebeler R, Spann NJ, Chen HJ, Bosmans LA, Gorbatenko A, van Wouw S, Zelcer N, Jacobs H, van Leeuwen F, de Winther MPJ. Willemsen L, et al. Among authors: van wouw s. Cell Rep. 2022 Nov 22;41(8):111703. doi: 10.1016/j.celrep.2022.111703. Cell Rep. 2022. PMID: 36417856 Free article.
Regulation of intestinal LDLR by the LXR-IDOL axis.
van Loon NM, van Wouw SAE, Ottenhoff R, Nelson JK, Kingma J, Scheij S, Moeton M, Zelcer N. van Loon NM, et al. Among authors: van wouw sae. Atherosclerosis. 2020 Dec;315:1-9. doi: 10.1016/j.atherosclerosis.2020.10.898. Epub 2020 Nov 9. Atherosclerosis. 2020. PMID: 33190106 Free article.