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Double-strand break toxicity is chromatin context independent.
Friskes A, Koob L, Krenning L, Severson TM, Koeleman ES, Vergara X, Schubert M, van den Berg J, Evers B, Manjón AG, Joosten S, Kim Y, Zwart W, Medema RH. Friskes A, et al. Among authors: van den berg j. Nucleic Acids Res. 2022 Sep 23;50(17):9930-9947. doi: 10.1093/nar/gkac758. Nucleic Acids Res. 2022. PMID: 36107780 Free PMC article.
Life or Death after a Break: What Determines the Choice?
Krenning L, van den Berg J, Medema RH. Krenning L, et al. Among authors: van den berg j. Mol Cell. 2019 Oct 17;76(2):346-358. doi: 10.1016/j.molcel.2019.08.023. Epub 2019 Sep 24. Mol Cell. 2019. PMID: 31561953 Free article. Review.
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance.
Schep R, Brinkman EK, Leemans C, Vergara X, van der Weide RH, Morris B, van Schaik T, Manzo SG, Peric-Hupkes D, van den Berg J, Beijersbergen RL, Medema RH, van Steensel B. Schep R, et al. Among authors: van den berg j, van der weide rh, van schaik t, van steensel b. Mol Cell. 2021 May 20;81(10):2216-2230.e10. doi: 10.1016/j.molcel.2021.03.032. Epub 2021 Apr 12. Mol Cell. 2021. PMID: 33848455 Free PMC article.
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells.
Hornsveld M, Feringa FM, Krenning L, van den Berg J, Smits LMM, Nguyen NBT, Rodríguez-Colman MJ, Dansen TB, Medema RH, Burgering BMT. Hornsveld M, et al. Among authors: van den berg j. Cell Rep. 2021 Jan 26;34(4):108675. doi: 10.1016/j.celrep.2020.108675. Cell Rep. 2021. PMID: 33503422 Free article.
Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.
Matas-Rico E, van Veen M, Leyton-Puig D, van den Berg J, Koster J, Kedziora KM, Molenaar B, Weerts MJ, de Rink I, Medema RH, Giepmans BN, Perrakis A, Jalink K, Versteeg R, Moolenaar WH. Matas-Rico E, et al. Among authors: van den berg j, van veen m. Cancer Cell. 2016 Oct 10;30(4):548-562. doi: 10.1016/j.ccell.2016.08.016. Epub 2016 Sep 29. Cancer Cell. 2016. PMID: 27693046 Free article.
1,293 results