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The aged hematopoietic system promotes hippocampal-dependent cognitive decline.
Smith LK, Verovskaya E, Bieri G, Horowitz AM, von Ungern-Sternberg SNI, Lin K, Seizer P, Passegué E, Villeda SA. Smith LK, et al. Among authors: von ungern sternberg sni. Aging Cell. 2020 Aug;19(8):e13192. doi: 10.1111/acel.13192. Epub 2020 Jul 21. Aging Cell. 2020. PMID: 33073926 Free PMC article.
The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis.
Heinzmann D, Bangert A, Müller AM, von Ungern-Sternberg SN, Emschermann F, Schönberger T, Chatterjee M, Mack AF, Klingel K, Kandolf R, Malesevic M, Borst O, Gawaz M, Langer HF, Katus H, Fischer G, May AE, Kaya Z, Seizer P. Heinzmann D, et al. PLoS One. 2015 Apr 20;10(4):e0124606. doi: 10.1371/journal.pone.0124606. eCollection 2015. PLoS One. 2015. PMID: 25894208 Free PMC article.
Circulating MicroRNA-21 Correlates With Left Atrial Low-Voltage Areas and Is Associated With Procedure Outcome in Patients Undergoing Atrial Fibrillation Ablation.
Zhou Q, Maleck C, von Ungern-Sternberg SNI, Neupane B, Heinzmann D, Marquardt J, Duckheim M, Scheckenbach C, Stimpfle F, Gawaz M, Schreieck J, Seizer P, Gramlich M. Zhou Q, et al. Among authors: von ungern sternberg sni. Circ Arrhythm Electrophysiol. 2018 Jun;11(6):e006242. doi: 10.1161/CIRCEP.118.006242. Circ Arrhythm Electrophysiol. 2018. PMID: 29848477 Free PMC article.
Platelet surface expression of cyclophilin A is associated with increased mortality in patients with symptomatic coronary artery disease.
Rath D, von Ungern-Sternberg S, Heinzmann D, Sigle M, Monzien M, Horstmann K, Schaeffeler E, Winter S, Müller K, Groga-Bada P, Zdanyte M, Borst O, Zernecke A, Gawaz M, Martus P, Schwab M, Geisler T, Seizer P. Rath D, et al. J Thromb Haemost. 2020 Jan;18(1):234-242. doi: 10.1111/jth.14635. Epub 2019 Oct 20. J Thromb Haemost. 2020. PMID: 31519036 Free article.
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
von Ungern-Sternberg SNI, Vogel S, Walker-Allgaier B, Geue S, Maurer A, Wild AM, Münzer P, Chatterjee M, Heinzmann D, Kremmer E, Borst O, Loughran P, Zernecke A, Neal MD, Billiar TR, Gawaz M, Seizer P. von Ungern-Sternberg SNI, et al. Thromb Haemost. 2017 Nov;117(11):2063-2078. doi: 10.1160/TH17-01-0067. Epub 2017 Nov 30. Thromb Haemost. 2017. PMID: 28981554 Free PMC article.
ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury.
Rohlfing AK, Kolb K, Sigle M, Ziegler M, Bild A, Münzer P, Sudmann J, Dicenta V, Harm T, Manke MC, Geue S, Kremser M, Chatterjee M, Liang C, von Eysmondt H, Dandekar T, Heinzmann D, Günter M, von Ungern-Sternberg S, Büttcher M, Castor T, Mencl S, Langhauser F, Sies K, Ashour D, Beker MC, Lämmerhofer M, Autenrieth SE, Schäffer TE, Laufer S, Szklanna P, Maguire P, Heikenwalder M, Müller KAL, Hermann DM, Kilic E, Stumm R, Ramos G, Kleinschnitz C, Borst O, Langer HF, Rath D, Gawaz M. Rohlfing AK, et al. Nat Commun. 2022 Apr 5;13(1):1823. doi: 10.1038/s41467-022-29341-1. Nat Commun. 2022. PMID: 35383158 Free PMC article.
Cyclophilin A is a ligand for RAGE in thrombo-inflammation.
Seizer P, von Ungern-Sternberg SNI, Haug V, Dicenta V, Rosa A, Butt E, Nöthel M, Rohlfing AK, Sigle M, Nawroth PP, Nussbaum C, Sperandio M, Kusch C, Meub M, Sauer M, Münzer P, Bieber K, Stanger A, Mack AF, Huber R, Brand K, Lehners M, Feil R, Poso A, Krutzke K, Schäffer TE, Nieswandt B, Borst O, May AE, Zernecke A, Gawaz M, Heinzmann D. Seizer P, et al. Among authors: von ungern sternberg sni. Cardiovasc Res. 2024 Mar 30;120(4):385-402. doi: 10.1093/cvr/cvad189. Cardiovasc Res. 2024. PMID: 38175781
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