Dissection of conformationally restricted inhibitors binding to a beta-glucosidase

Chembiochem. 2006 May;7(5):738-42. doi: 10.1002/cbic.200600005.

Authors

Tracey M Gloster¹, Robert Madsen, Gideon J Davies

Affiliation

¹ Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York, YO10 5YW, UK.

PMID: 16628756
DOI: 10.1002/cbic.200600005

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Binding Sites
Carbohydrate Conformation
Crystallography, X-Ray
Enzyme Inhibitors / chemistry
Enzyme Inhibitors / pharmacology*
Hydrogen-Ion Concentration
Kinetics
Models, Molecular
Molecular Conformation
Protein Binding
Protein Structure, Tertiary
Structure-Activity Relationship
beta-Glucosidase / antagonists & inhibitors*
beta-Glucosidase / chemistry

Substances

Enzyme Inhibitors
beta-Glucosidase