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Year | Number of Results |
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2015 | 1 |
2016 | 1 |
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2018 | 1 |
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Kynurenine-3-monooxygenase: a review of structure, mechanism, and inhibitors.
Drug Discov Today. 2016 Feb;21(2):315-24. doi: 10.1016/j.drudis.2015.11.001. Epub 2015 Nov 14.
Drug Discov Today. 2016.
PMID: 26589832
Review.
Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.
Walker AL, Ancellin N, Beaufils B, Bergeal M, Binnie M, Bouillot A, Clapham D, Denis A, Haslam CP, Holmes DS, Hutchinson JP, Liddle J, McBride A, Mirguet O, Mowat CG, Rowland P, Tiberghien N, Trottet L, Uings I, Webster SP, Zheng X, Mole DJ.
Walker AL, et al.
J Med Chem. 2017 Apr 27;60(8):3383-3404. doi: 10.1021/acs.jmedchem.7b00055. Epub 2017 Apr 11.
J Med Chem. 2017.
PMID: 28398044
Free article.
Item in Clipboard
Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase.
Hutchinson JP, Rowland P, Taylor MRD, Christodoulou EM, Haslam C, Hobbs CI, Holmes DS, Homes P, Liddle J, Mole DJ, Uings I, Walker AL, Webster SP, Mowat CG, Chung CW.
Hutchinson JP, et al.
Nat Commun. 2017 Jun 12;8:15827. doi: 10.1038/ncomms15827.
Nat Commun. 2017.
PMID: 28604669
Free PMC article.
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Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048.
Gao J, Yao L, Xia T, Liao X, Zhu D, Xiang Y.
Gao J, et al.
FASEB J. 2018 Apr;32(4):2036-2045. doi: 10.1096/fj.201700397RR. Epub 2018 Jan 5.
FASEB J. 2018.
PMID: 29208702
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