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A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate.
Nat Commun. 2017 Aug 22;8(1):316. doi: 10.1038/s41467-017-00154-x.
Nat Commun. 2017.
PMID: 28827772
Free PMC article.
Solution of the multistep pathway for assembly of corynanthean, strychnos, iboga, and aspidosperma monoterpenoid indole alkaloids from 19E-geissoschizine.
Qu Y, Easson MEAM, Simionescu R, Hajicek J, Thamm AMK, Salim V, De Luca V.
Qu Y, et al.
Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3180-3185. doi: 10.1073/pnas.1719979115. Epub 2018 Mar 6.
Proc Natl Acad Sci U S A. 2018.
PMID: 29511102
Free PMC article.
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