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Solution of the multistep pathway for assembly of corynanthean, strychnos, iboga, and aspidosperma monoterpenoid indole alkaloids from 19E-geissoschizine.
Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3180-3185. doi: 10.1073/pnas.1719979115. Epub 2018 Mar 6.
Proc Natl Acad Sci U S A. 2018.
PMID: 29511102
Free PMC article.
A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate.
Tatsis EC, Carqueijeiro I, Dugé de Bernonville T, Franke J, Dang TT, Oudin A, Lanoue A, Lafontaine F, Stavrinides AK, Clastre M, Courdavault V, O'Connor SE.
Tatsis EC, et al.
Nat Commun. 2017 Aug 22;8(1):316. doi: 10.1038/s41467-017-00154-x.
Nat Commun. 2017.
PMID: 28827772
Free PMC article.
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