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Page 1
Microglia-derived extracellular vesicles trigger age-related neurodegeneration upon DNA damage.
Arvanitaki ES, Goulielmaki E, Gkirtzimanaki K, Niotis G, Tsakani E, Nenedaki E, Rouska I, Kefalogianni M, Xydias D, Kalafatakis I, Psilodimitrakopoulos S, Karagogeos D, Schumacher B, Stratakis E, Garinis GA. Arvanitaki ES, et al. Among authors: gkirtzimanaki k. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2317402121. doi: 10.1073/pnas.2317402121. Epub 2024 Apr 18. Proc Natl Acad Sci U S A. 2024. PMID: 38635632
NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE.
Georgakis S, Gkirtzimanaki K, Papadaki G, Gakiopoulou H, Drakos E, Eloranta ML, Makridakis M, Kontostathi G, Zoidakis J, Baira E, Rönnblom L, Boumpas DT, Sidiropoulos P, Verginis P, Bertsias G. Georgakis S, et al. Among authors: gkirtzimanaki k. JCI Insight. 2021 Nov 8;6(21):e147671. doi: 10.1172/jci.insight.147671. JCI Insight. 2021. PMID: 34554930 Free PMC article.
TPL2 kinase is a suppressor of lung carcinogenesis.
Gkirtzimanaki K, Gkouskou KK, Oleksiewicz U, Nikolaidis G, Vyrla D, Liontos M, Pelekanou V, Kanellis DC, Evangelou K, Stathopoulos EN, Field JK, Tsichlis PN, Gorgoulis V, Liloglou T, Eliopoulos AG. Gkirtzimanaki K, et al. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1470-9. doi: 10.1073/pnas.1215938110. Epub 2013 Mar 26. Proc Natl Acad Sci U S A. 2013. PMID: 23533274 Free PMC article.
CD151 regulates tumorigenesis by modulating the communication between tumor cells and endothelium.
Sadej R, Romanska H, Baldwin G, Gkirtzimanaki K, Novitskaya V, Filer AD, Krcova Z, Kusinska R, Ehrmann J, Buckley CD, Kordek R, Potemski P, Eliopoulos AG, Lalani el-N, Berditchevski F. Sadej R, et al. Among authors: gkirtzimanaki k. Mol Cancer Res. 2009 Jun;7(6):787-98. doi: 10.1158/1541-7786.MCR-08-0574. Epub 2009 Jun 16. Mol Cancer Res. 2009. PMID: 19531562 Free article.
Suppression of integrin alpha3beta1 in breast cancer cells reduces cyclooxygenase-2 gene expression and inhibits tumorigenesis, invasion, and cross-talk to endothelial cells.
Mitchell K, Svenson KB, Longmate WM, Gkirtzimanaki K, Sadej R, Wang X, Zhao J, Eliopoulos AG, Berditchevski F, Dipersio CM. Mitchell K, et al. Among authors: gkirtzimanaki k. Cancer Res. 2010 Aug 1;70(15):6359-67. doi: 10.1158/0008-5472.CAN-09-4283. Epub 2010 Jul 14. Cancer Res. 2010. PMID: 20631072 Free PMC article.