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Year Number of Results
2014 1
2017 1
2018 1
2019 1
2020 4
2021 3
2022 2
2024 0

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11 results

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Page 1
Regulation of mTORC1 by Upstream Stimuli.
Melick CH, Jewell JL. Melick CH, et al. Genes (Basel). 2020 Aug 25;11(9):989. doi: 10.3390/genes11090989. Genes (Basel). 2020. PMID: 32854217 Free PMC article. Review.
SNAT7 regulates mTORC1 via macropinocytosis.
Meng D, Yang Q, Jeong MH, Curukovic A, Tiwary S, Melick CH, Lama-Sherpa TD, Wang H, Huerta-Rosario M, Urquhart G, Zacharias LG, Lewis C, DeBerardinis RJ, Jewell JL. Meng D, et al. Among authors: melick ch. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2123261119. doi: 10.1073/pnas.2123261119. Epub 2022 May 13. Proc Natl Acad Sci U S A. 2022. PMID: 35561222 Free PMC article.
ArfGAP1 inhibits mTORC1 lysosomal localization and activation.
Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. Meng D, et al. Among authors: melick ch. EMBO J. 2021 Jun 15;40(12):e106412. doi: 10.15252/embj.2020106412. Epub 2021 May 14. EMBO J. 2021. PMID: 33988249 Free PMC article.
AKAP13 couples GPCR signaling to mTORC1 inhibition.
Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. Zhang S, et al. Among authors: melick ch. PLoS Genet. 2021 Oct 21;17(10):e1009832. doi: 10.1371/journal.pgen.1009832. eCollection 2021 Oct. PLoS Genet. 2021. PMID: 34673774 Free PMC article.
Glutamine and asparagine activate mTORC1 independently of Rag GTPases.
Meng D, Yang Q, Wang H, Melick CH, Navlani R, Frank AR, Jewell JL. Meng D, et al. Among authors: melick ch. J Biol Chem. 2020 Mar 6;295(10):2890-2899. doi: 10.1074/jbc.AC119.011578. Epub 2020 Feb 4. J Biol Chem. 2020. PMID: 32019866 Free PMC article.
GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.
Jewell JL, Fu V, Hong AW, Yu FX, Meng D, Melick CH, Wang H, Lam WM, Yuan HX, Taylor SS, Guan KL. Jewell JL, et al. Among authors: melick ch. Elife. 2019 May 21;8:e43038. doi: 10.7554/eLife.43038. Elife. 2019. PMID: 31112131 Free PMC article.
11 results