Nano/Microfluidics for diagnosis of infectious diseases in developing countries

Adv Drug Deliv Rev. 2010 Mar 18;62(4-5):449-57. doi: 10.1016/j.addr.2009.11.016. Epub 2009 Nov 30.

Abstract

Nano/Microfluidic technologies are emerging as powerful enabling tools for diagnosis and monitoring of infectious diseases in both developed and developing countries. Miniaturized nano/microfluidic platforms that precisely manipulate small fluid volumes can be used to enable medical diagnosis in a more rapid and accurate manner. In particular, these nano/microfluidic diagnostic technologies are potentially applicable to global health applications, since they are disposable, inexpensive, portable, and easy-to-use for detection of infectious diseases. In this paper, we review recent advances in nano/microfluidic technologies for clinical point-of-care applications at resource-limited settings in developing countries.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Developing Countries*
  • Flow Cytometry
  • HIV Infections / diagnosis
  • Humans
  • Immunoassay
  • Infections / diagnosis*
  • Malaria / diagnosis
  • Microcomputers
  • Microfluidics / trends*
  • Nanotechnology / trends*
  • Tuberculosis / diagnosis