DNA and cell cycle analysis of retinoblastoma

Curr Eye Res. 1987 Sep;6(9):1133-9. doi: 10.3109/02713688709034886.

Abstract

We retrospectively analyzed archival retinoblastomas from 44 eyes. The percentage of cycling cells were increased in younger patients, those with advanced disease, and cases with poor prognosis. These data suggest that all cell cycle studies may yield important insights in retinoblastoma.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aging / physiology
  • Aneuploidy
  • Cell Cycle
  • DNA / metabolism*
  • Eye Neoplasms / genetics*
  • Eye Neoplasms / pathology
  • Humans
  • Retinoblastoma / genetics*
  • Retinoblastoma / pathology
  • Retrospective Studies

Substances

  • DNA