Iwatsubo T - Search Results

1

Selective loss of nigral dopamine neurons induced by overexpression of truncated human alpha-synuclein in mice.

Wakamatsu M, Ishii A, Iwata S, Sakagami J, Ukai Y, Ono M, Kanbe D, Muramatsu S, Kobayashi K, Iwatsubo T, Yoshimoto M. Wakamatsu M, et al. Among authors: iwatsubo t. Neurobiol Aging. 2008 Apr;29(4):574-85. doi: 10.1016/j.neurobiolaging.2006.11.017. Epub 2006 Dec 14. Neurobiol Aging. 2008. PMID: 17174013

2

Accumulation of phosphorylated alpha-synuclein in dopaminergic neurons of transgenic mice that express human alpha-synuclein.

Wakamatsu M, Ishii A, Ukai Y, Sakagami J, Iwata S, Ono M, Matsumoto K, Nakamura A, Tada N, Kobayashi K, Iwatsubo T, Yoshimoto M. Wakamatsu M, et al. Among authors: iwatsubo t. J Neurosci Res. 2007 Jun;85(8):1819-25. doi: 10.1002/jnr.21310. J Neurosci Res. 2007. PMID: 17465029

3

Accumulation of phosphorylated alpha-synuclein in the brain and peripheral ganglia of patients with multiple system atrophy.

Nishie M, Mori F, Fujiwara H, Hasegawa M, Yoshimoto M, Iwatsubo T, Takahashi H, Wakabayashi K. Nishie M, et al. Among authors: iwatsubo t. Acta Neuropathol. 2004 Apr;107(4):292-8. doi: 10.1007/s00401-003-0811-1. Epub 2004 Jan 14. Acta Neuropathol. 2004. PMID: 14722716

4

Alpha-synuclein accumulates in Purkinje cells in Lewy body disease but not in multiple system atrophy.

Mori F, Piao YS, Hayashi S, Fujiwara H, Hasegawa M, Yoshimoto M, Iwatsubo T, Takahashi H, Wakabayashi K. Mori F, et al. Among authors: iwatsubo t. J Neuropathol Exp Neurol. 2003 Aug;62(8):812-9. doi: 10.1093/jnen/62.8.812. J Neuropathol Exp Neurol. 2003. PMID: 14503637

5

Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease.

Yamada M, Iwatsubo T, Mizuno Y, Mochizuki H. Yamada M, et al. Among authors: iwatsubo t. J Neurochem. 2004 Oct;91(2):451-61. doi: 10.1111/j.1471-4159.2004.02728.x. J Neurochem. 2004. PMID: 15447678 Free article.

6

Familial Parkinson mutant alpha-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans.

Kuwahara T, Koyama A, Gengyo-Ando K, Masuda M, Kowa H, Tsunoda M, Mitani S, Iwatsubo T. Kuwahara T, et al. Among authors: iwatsubo t. J Biol Chem. 2006 Jan 6;281(1):334-40. doi: 10.1074/jbc.M504860200. Epub 2005 Oct 31. J Biol Chem. 2006. PMID: 16260788 Free article.

7

Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila.

Takahashi M, Kanuka H, Fujiwara H, Koyama A, Hasegawa M, Miura M, Iwatsubo T. Takahashi M, et al. Among authors: iwatsubo t. Neurosci Lett. 2003 Jan 23;336(3):155-8. doi: 10.1016/s0304-3940(02)01258-2. Neurosci Lett. 2003. PMID: 12505616

8

alpha-Synuclein is phosphorylated in synucleinopathy lesions.

Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T. Fujiwara H, et al. Among authors: iwatsubo t. Nat Cell Biol. 2002 Feb;4(2):160-4. doi: 10.1038/ncb748. Nat Cell Biol. 2002. PMID: 11813001

9

Ubiquitination of alpha-synuclein.

Nonaka T, Iwatsubo T, Hasegawa M. Nonaka T, et al. Among authors: iwatsubo t. Biochemistry. 2005 Jan 11;44(1):361-8. doi: 10.1021/bi0485528. Biochemistry. 2005. PMID: 15628878

10

Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells.

Machida Y, Chiba T, Takayanagi A, Tanaka Y, Asanuma M, Ogawa N, Koyama A, Iwatsubo T, Ito S, Jansen PH, Shimizu N, Tanaka K, Mizuno Y, Hattori N. Machida Y, et al. Among authors: iwatsubo t. Biochem Biophys Res Commun. 2005 Jun 24;332(1):233-40. doi: 10.1016/j.bbrc.2005.04.124. Biochem Biophys Res Commun. 2005. PMID: 15896322

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