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The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments.
Ravenstijn PG, Merlini M, Hameetman M, Murray TK, Ward MA, Lewis H, Ball G, Mottart C, de Ville de Goyet C, Lemarchand T, van Belle K, O'Neill MJ, Danhof M, de Lange EC. Ravenstijn PG, et al. Among authors: murray tk. J Pharmacol Toxicol Methods. 2008 Mar-Apr;57(2):114-30. doi: 10.1016/j.vascn.2007.10.003. Epub 2007 Nov 13. J Pharmacol Toxicol Methods. 2008. PMID: 18155613
LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.
Murray TK, Whalley K, Robinson CS, Ward MA, Hicks CA, Lodge D, Vandergriff JL, Baumbarger P, Siuda E, Gates M, Ogden AM, Skolnick P, Zimmerman DM, Nisenbaum ES, Bleakman D, O'Neill MJ. Murray TK, et al. J Pharmacol Exp Ther. 2003 Aug;306(2):752-62. doi: 10.1124/jpet.103.049445. Epub 2003 May 2. J Pharmacol Exp Ther. 2003. PMID: 12730350
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity.
Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, Hutton ML, O'Neill MJ. Ahmed Z, et al. Among authors: murray tk. Acta Neuropathol. 2014 May;127(5):667-83. doi: 10.1007/s00401-014-1254-6. Epub 2014 Feb 16. Acta Neuropathol. 2014. PMID: 24531916 Free PMC article.
103 results