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CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane.
Kim SJ, Kwon MC, Ryu MJ, Chung HK, Tadi S, Kim YK, Kim JM, Lee SH, Park JH, Kweon GR, Ryu SW, Jo YS, Lee CH, Hatakeyama H, Goto Y, Yim YH, Chung J, Kong YY, Shong M. Kim SJ, et al. Among authors: kim yk, kim jm. Cell Metab. 2012 Aug 8;16(2):274-83. doi: 10.1016/j.cmet.2012.06.012. Epub 2012 Jul 19. Cell Metab. 2012. PMID: 22819524 Free article.
Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice.
Ryu MJ, Kim SJ, Kim YK, Choi MJ, Tadi S, Lee MH, Lee SE, Chung HK, Jung SB, Kim HJ, Jo YS, Kim KS, Lee SH, Kim JM, Kweon GR, Park KC, Lee JU, Kong YY, Lee CH, Chung J, Shong M. Ryu MJ, et al. Among authors: kim yk, kim hj, kim jm, kim sj, kim ks. PLoS Genet. 2013;9(3):e1003356. doi: 10.1371/journal.pgen.1003356. Epub 2013 Mar 14. PLoS Genet. 2013. PMID: 23516375 Free PMC article.
Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure.
Kim YK, Joung KH, Ryu MJ, Kim SJ, Kim H, Chung HK, Lee MH, Lee SE, Choi MJ, Chang JY, Hong HJ, Kim KS, Lee SH, Kweon GR, Kim H, Lee CH, Kim HJ, Shong M. Kim YK, et al. Among authors: kim h, kim hj, kim sj, kim ks. Diabetologia. 2015 Apr;58(4):771-80. doi: 10.1007/s00125-015-3506-y. Epub 2015 Feb 8. Diabetologia. 2015. PMID: 25660120
Dysregulation of Parkin-mediated mitophagy in thyroid Hürthle cell tumors.
Lee J, Ham S, Lee MH, Kim SJ, Park JH, Lee SE, Chang JY, Joung KH, Kim TY, Kim JM, Sul HJ, Kweon GR, Jo YS, Kim KS, Shong YK, Gasparre G, Chung JK, Porcelli AM, Shong M. Lee J, et al. Among authors: kim jm, kim ty, kim sj, kim ks. Carcinogenesis. 2015 Nov;36(11):1407-18. doi: 10.1093/carcin/bgv122. Epub 2015 Sep 8. Carcinogenesis. 2015. PMID: 26354775
Thyroid dysfunction associated with follicular cell steatosis in obese male mice and humans.
Lee MH, Lee JU, Joung KH, Kim YK, Ryu MJ, Lee SE, Kim SJ, Chung HK, Choi MJ, Chang JY, Lee SH, Kweon GR, Kim HJ, Kim KS, Kim SM, Jo YS, Park J, Cheng SY, Shong M. Lee MH, et al. Among authors: kim yk, kim hj, kim sj, kim ks, kim sm. Endocrinology. 2015 Mar;156(3):1181-93. doi: 10.1210/en.2014-1670. Epub 2015 Jan 2. Endocrinology. 2015. PMID: 25555091 Free PMC article.
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
Chung HK, Ryu D, Kim KS, Chang JY, Kim YK, Yi HS, Kang SG, Choi MJ, Lee SE, Jung SB, Ryu MJ, Kim SJ, Kweon GR, Kim H, Hwang JH, Lee CH, Lee SJ, Wall CE, Downes M, Evans RM, Auwerx J, Shong M. Chung HK, et al. Among authors: kim h, kim yk, kim sj, kim ks. J Cell Biol. 2017 Jan 2;216(1):149-165. doi: 10.1083/jcb.201607110. Epub 2016 Dec 16. J Cell Biol. 2017. PMID: 27986797 Free PMC article.
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