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Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Takahashi J, Eguchi S, Yamashita A, Tomio K, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Sato M, et al. Among authors: yamashita a. Oncotarget. 2016 May 31;7(22):33297-305. doi: 10.18632/oncotarget.8947. Oncotarget. 2016. PMID: 27120812 Free PMC article.
Decreased expression of the plasminogen activator inhibitor type 1 is involved in degradation of extracellular matrix surrounding cervical cancer stem cells.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Takahashi J, Kojima S, Yamashita A, Tomio K, Nagamatsu T, Wada-Hiraike O, Oda K, Osuga Y, Fujii T. Sato M, et al. Among authors: yamashita a. Int J Oncol. 2016 Feb;48(2):829-35. doi: 10.3892/ijo.2015.3283. Epub 2015 Dec 9. Int J Oncol. 2016. PMID: 26676222
Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis.
Fujimoto A, Kawana K, Taguchi A, Adachi K, Sato M, Nakamura H, Ogishima J, Yoshida M, Inoue T, Nishida H, Tomio K, Yamashita A, Matsumoto Y, Arimoto T, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Fujimoto A, et al. Among authors: yamashita a. Oncotarget. 2016 Aug 9;7(32):51854-51864. doi: 10.18632/oncotarget.10126. Oncotarget. 2016. PMID: 27322083 Free PMC article.
Low uptake of fluorodeoxyglucose in positron emission tomography/computed tomography in ovarian clear cell carcinoma may reflect glutaminolysis of its cancer stem cell-like properties.
Sato M, Kawana K, Adachi K, Fujimoto A, Taguchi A, Fujikawa T, Yoshida M, Nakamura H, Nishida H, Inoue T, Ogishima J, Eguchi S, Yamashita A, Tomio K, Arimoto T, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Sato M, et al. Among authors: yamashita a. Oncol Rep. 2017 Mar;37(3):1883-1888. doi: 10.3892/or.2017.5398. Epub 2017 Jan 20. Oncol Rep. 2017. PMID: 28112360
Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Ogishima J, Eguchi S, Yamashita A, Tomio K, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Sato M, et al. Among authors: yamashita a. Int J Oncol. 2017 Apr;50(4):1431-1438. doi: 10.3892/ijo.2017.3891. Epub 2017 Feb 23. Int J Oncol. 2017. PMID: 28259988
Regeneration of cervical reserve cell-like cells from human induced pluripotent stem cells (iPSCs): A new approach to finding targets for cervical cancer stem cell treatment.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Ogishima J, Eguchi S, Yamashita A, Tomio K, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Sato M, et al. Among authors: yamashita a. Oncotarget. 2017 Jun 20;8(25):40935-40945. doi: 10.18632/oncotarget.16783. Oncotarget. 2017. PMID: 28402962 Free PMC article.
Therapeutic significance of targeting survivin in cervical cancer and possibility of combination therapy with TRAIL.
Nakamura H, Taguchi A, Kawana K, Baba S, Kawata A, Yoshida M, Fujimoto A, Ogishima J, Sato M, Inoue T, Nishida H, Furuya H, Yamashita A, Eguchi S, Tomio K, Mori-Uchino M, Adachi K, Arimoto T, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Nakamura H, et al. Among authors: yamashita a. Oncotarget. 2018 Feb 5;9(17):13451-13461. doi: 10.18632/oncotarget.24413. eCollection 2018 Mar 2. Oncotarget. 2018. PMID: 29568369 Free PMC article.
The prevalence of cervical regulatory T cells in HPV-related cervical intraepithelial neoplasia (CIN) correlates inversely with spontaneous regression of CIN.
Kojima S, Kawana K, Tomio K, Yamashita A, Taguchi A, Miura S, Adachi K, Nagamatsu T, Nagasaka K, Matsumoto Y, Arimoto T, Oda K, Wada-Hiraike O, Yano T, Taketani Y, Fujii T, Schust DJ, Kozuma S. Kojima S, et al. Among authors: yamashita a. Am J Reprod Immunol. 2013 Feb;69(2):134-41. doi: 10.1111/aji.12030. Epub 2012 Oct 11. Am J Reprod Immunol. 2013. PMID: 23057776
Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo.
Taguchi A, Kawana K, Tomio K, Yamashita A, Isobe Y, Nagasaka K, Koga K, Inoue T, Nishida H, Kojima S, Adachi K, Matsumoto Y, Arimoto T, Wada-Hiraike O, Oda K, Kang JX, Arai H, Arita M, Osuga Y, Fujii T. Taguchi A, et al. Among authors: yamashita a. PLoS One. 2014 Feb 27;9(2):e89605. doi: 10.1371/journal.pone.0089605. eCollection 2014. PLoS One. 2014. PMID: 24586907 Free PMC article.
Oral vaccination against HPV E7 for treatment of cervical intraepithelial neoplasia grade 3 (CIN3) elicits E7-specific mucosal immunity in the cervix of CIN3 patients.
Kawana K, Adachi K, Kojima S, Taguchi A, Tomio K, Yamashita A, Nishida H, Nagasaka K, Arimoto T, Yokoyama T, Wada-Hiraike O, Oda K, Sewaki T, Osuga Y, Fujii T. Kawana K, et al. Among authors: yamashita a. Vaccine. 2014 Oct 29;32(47):6233-9. doi: 10.1016/j.vaccine.2014.09.020. Epub 2014 Sep 22. Vaccine. 2014. PMID: 25258102 Clinical Trial.
1,757 results