Effects of entrapment in liposomes on the distribution, degradation and effectiveness of methotrexate in vivo

Ann N Y Acad Sci. 1978;308:395-410. doi: 10.1111/j.1749-6632.1978.tb22037.x.
No abstract available

MeSH terms

  • Animals
  • Guinea Pigs
  • Haplorhini
  • Kinetics
  • Leukemia L1210 / drug therapy
  • Liposomes / therapeutic use*
  • Liver / metabolism
  • Macaca fascicularis
  • Metabolic Clearance Rate
  • Methotrexate / administration & dosage*
  • Methotrexate / metabolism
  • Pharmaceutical Vehicles*
  • Spleen / metabolism
  • Tissue Distribution

Substances

  • Liposomes
  • Pharmaceutical Vehicles
  • Methotrexate