Combined administration of low dose heparin and aspirin as prophylaxis of deep vein thrombosis after hip joint surgery

Haemostasis. 1976;5(4):250-7. doi: 10.1159/000214140.


The study was carried out on 75 patients undergoing hip joint surgery. The efficacy of a prophylaxis of deep vein thrombosis (DVT) by acetylsalicyclic lysine (ASL) and by a low dose heparin (LDH) combined with the ASL treatment was investigated using the 125I-fibrinogen test. DVT was not significantly decreased by the ASL application (53%) compared to the controls (60%). DVT occurred significantly less under the combined administration (27%) than in the other two groups.

MeSH terms

  • Adult
  • Aged
  • Aspirin / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Heparin / therapeutic use*
  • Hip Joint / surgery*
  • Humans
  • Male
  • Middle Aged
  • Popliteal Vein
  • Pulmonary Embolism / drug therapy
  • Thrombophlebitis / drug therapy*


  • Heparin
  • Aspirin