Quantitative genetics of energy balance--lessons from animal models

Obes Res. 1999 Jan;7(1):106-10. doi: 10.1002/j.1550-8528.1999.tb00397.x.


Evidence for quantitative genetic variation in components of energy balance in animals is overwhelming. Much of this evidence is drawn from livestock species and relevant rodent models, especially long-term selection lines. This mini-review summarizes findings from several animal studies that have characterized quantitative genetic variation in energy intake and energy expenditure. Applications of this information toward understanding and treatment of human obesity are explored.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Domestic / genetics*
  • Energy Intake / genetics*
  • Energy Metabolism / genetics*
  • Genetic Variation
  • Humans
  • Mice
  • Obesity / genetics
  • Quantitative Trait, Heritable*
  • Selection, Genetic