Synaptic connections to phrenic motoneurons in the decerebrate rat

Adv Exp Med Biol. 1998;450:51-9. doi: 10.1007/978-1-4757-9077-1_11.


Phrenic motoneuron membrane potential trajectories in decerebrate rats exhibit three stages; depolarisation during inspiration, a decreased depolarisation during early expiration and hyperpolarization during late expiration. These trajectories are a result of excitation by ventral-group medullary inspiratory neurons and upper-cervical inspiratory neurons during inspiration and the early part of expiration, and inhibition from Bötzinger-complex expiratory neurons during the late part of expiration.

MeSH terms

  • Animals
  • Dogs
  • Motor Neurons / physiology*
  • Phrenic Nerve / physiology*
  • Rats
  • Respiratory Mechanics / physiology*
  • Respiratory System / innervation
  • Species Specificity
  • Synaptic Transmission / physiology*