Prospective randomized multicentre study of laparoscopic versus open appendicectomy

Br J Surg. 1999 Jan;86(1):48-53. doi: 10.1046/j.1365-2168.1999.00971.x.

Abstract

Background: A prospective randomized multicentre study was performed to compare the outcome of laparoscopic and open appendicectomy in patients with suspected acute appendicitis.

Methods: A total of 523 patients was randomized, but because of 23 withdrawals the outcome in 500 patients is reported, 244 in the laparoscopic group and 256 in the open group.

Results: Patients having laparoscopic appendicectomy recovered more quickly than those having open surgery (13 versus 21 days, P < 0.001). There was no significant difference in duration of sick leave after operation (laparoscopic group 11 days versus open group 14 days). Postoperative pain (at 24 h, 7 days and 14 days) was less after laparoscopic operations and a functional index 1 week after operation was more favourable in these patients (P < 0.001). Operating time was significantly longer in the laparoscopic group (60 versus 35 min, P < 0.01). Hospital stay and complications did not differ between the groups. Thirty laparoscopic procedures (12 per cent) were converted to open appendicectomy.

Conclusion: Laparoscopic appendicectomy is as safe as open appendicectomy and has the advantage of allowing a quicker recovery.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Aged
  • Appendectomy / adverse effects
  • Appendectomy / methods*
  • Appendicitis / surgery*
  • Follow-Up Studies
  • Humans
  • Laparoscopy / adverse effects
  • Laparoscopy / methods*
  • Middle Aged
  • Pain, Postoperative / etiology
  • Prospective Studies
  • Sick Leave / statistics & numerical data
  • Surgical Wound Infection / etiology
  • Time Factors