Complete remission of a diffuse pontine glioma

Neuropediatrics. 1998 Dec;29(6):328-30. doi: 10.1055/s-2007-973589.


A patient is described in whom a large diffuse glioma of the pons extending into the midbrain was diagnosed at the age of 2 years. Biopsy showed a fibrillary astrocytoma. After shunting of a hydrocephalus, the clinical symptoms abated without conventional therapy. Repeated MRI studies showed a continuous decrease of the tumour which was no longer visible when the patient was 6.6 years old. In reviews on spontaneous remissions of oncologic disorders we were unable to find a case of a biologically benign brain stem tumour. There is one isolated report on a similar case, though without histologic documentation.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Brain Neoplasms* / pathology
  • Brain Neoplasms* / physiopathology
  • Brain Neoplasms* / therapy
  • Follow-Up Studies
  • Glioma* / pathology
  • Glioma* / physiopathology
  • Glioma* / therapy
  • Humans
  • Hydrocephalus / therapy
  • Infant
  • Male
  • Mistletoe
  • Neoplasm Regression, Spontaneous*
  • Phytotherapy
  • Plant Extracts / therapeutic use
  • Plant Proteins*
  • Plants, Medicinal
  • Pons*
  • Treatment Outcome


  • Antineoplastic Agents, Phytogenic
  • Plant Extracts
  • Plant Proteins
  • viscum album peptide