Surface protein adhesins of Staphylococcus aureus

Trends Microbiol. 1998 Dec;6(12):484-8. doi: 10.1016/s0966-842x(98)01400-0.


Staphylococcus aureus can colonize the host to initiate infection by adhering to components of the extracellular matrix. Adherence is mediated by surface protein adhesins (MSCRAMMs). Ligand binding by these fibronectin-, fibrinogen- and collagen-binding proteins occurs by distinct mechanisms that are being investigated at the molecular level.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adhesins, Bacterial / metabolism*
  • Animals
  • Bacterial Proteins / metabolism*
  • Carrier Proteins / metabolism
  • Collagen / metabolism
  • Fibronectins / metabolism
  • Humans
  • Phosphate-Binding Proteins
  • Staphylococcus aureus / physiology*


  • Adhesins, Bacterial
  • Bacterial Proteins
  • CAVIN2 protein, human
  • Carrier Proteins
  • Fibronectins
  • Phosphate-Binding Proteins
  • adhesin, Staphylococcus aureus
  • Collagen