Surface protein adhesins of Staphylococcus aureus

Trends Microbiol. 1998 Dec;6(12):484-8. doi: 10.1016/s0966-842x(98)01400-0.

Abstract

Staphylococcus aureus can colonize the host to initiate infection by adhering to components of the extracellular matrix. Adherence is mediated by surface protein adhesins (MSCRAMMs). Ligand binding by these fibronectin-, fibrinogen- and collagen-binding proteins occurs by distinct mechanisms that are being investigated at the molecular level.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adhesins, Bacterial / metabolism*
  • Animals
  • Bacterial Proteins / metabolism*
  • Carrier Proteins / metabolism
  • Collagen / metabolism
  • Fibronectins / metabolism
  • Humans
  • Phosphate-Binding Proteins
  • Staphylococcus aureus / physiology*

Substances

  • Adhesins, Bacterial
  • Bacterial Proteins
  • CAVIN2 protein, human
  • Carrier Proteins
  • Fibronectins
  • Phosphate-Binding Proteins
  • adhesin, Staphylococcus aureus
  • Collagen