Operative results after primary and secondary debulking-operations in advanced ovarian cancer (AOC)

J Obstet Gynaecol Res. 1998 Dec;24(6):447-51. doi: 10.1111/j.1447-0756.1998.tb00122.x.


Objective: To assess the role of primary and secondary radical surgery in advanced ovarian cancer (AOC).

Design: Retrospective study.

Methods: One hundred and fifty-one patients with AOC (FIGO III/IV) underwent altogether 191 extended multivisceral operations between 1/1992 and 2/1998. The statistic analysis compared the primary with the secondary operations.

Results: One hundred and seventeen patients had a primary, 63 patients had a secondary and 18 patients a tertiary operation because of relapse of ovarian cancer. Surgical procedures entailed respectively: small-bowel-resection (21%/48%), colon resection (39%/58%), colostomy (9%/11%), ileostomy (2%/4%), ileum-pouch (0%/6), splenectomy (3%/3%), pelvic floor-covering (4%/6%), peritoneal removal (24%/21%), infrared contact coagulation (4%/6%). Seventy-five percent of the patients had no complications: relaparotomy (3%/3%), fistula (3%/6%), short-bowel-syndrome (5%/11%), postoperatively mortality (2%/6%). Postoperative tumor-free were 26%/22%, 57% and 65% had residual disease < or = 2 cm, 16%/13% > 2 cm.

Conclusions: Radical multivisceral surgery is feasible, safe and efficient in primary as well in secondary situation of advanced ovarian cancer.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Middle Aged
  • Neoplasm Recurrence, Local / surgery*
  • Ovarian Neoplasms / surgery*
  • Postoperative Complications
  • Retrospective Studies
  • Treatment Outcome