The Diverse Habitats of Obligate Intracellular Parasites

Curr Opin Microbiol. 1998 Feb;1(1):82-7. doi: 10.1016/s1369-5274(98)80146-x.

Abstract

Bacterial obligate intracellular parasites have evolved diverse mechanisms for evasion of host cellular defenses. These mechanisms involve adaptations for survival in distinct intracellular compartments. Intracellular niches inhabited by obligate intracellular parasites include the cytoplasm, arrested early endosomes, lysosomes, and vesicles that do not fuse with the endosomal compartment but intersect with an exocytic pathway.

Publication types

  • Review

MeSH terms

  • Chlamydia / pathogenicity
  • Chlamydia / physiology*
  • Chlamydia Infections / microbiology
  • Chlamydia Infections / physiopathology
  • Coxiella / pathogenicity
  • Coxiella / physiology
  • Ehrlichia / pathogenicity
  • Ehrlichia / physiology
  • Humans
  • Rickettsia / pathogenicity
  • Rickettsia / physiology
  • Rickettsiaceae / pathogenicity
  • Rickettsiaceae / physiology*
  • Rickettsiaceae Infections / microbiology
  • Rickettsiaceae Infections / physiopathology
  • Vacuoles / metabolism